Evidence map›Paper›PMID 25342311›Full record

ArticleWorld journal of microbiology & biotechnology2015

Protective roles of osmotic stress-resistant Hos3 against oxidative, nitrosative and nutritional stresses in Schizosaccharomyces pombe.

Chang-Jin Lim, Hannah Jo, Kyunghoon Kim

Abstract read
PubMed Publisher
In one paragraph

Article in World journal of microbiology & biotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Chang-Jin LimDepartment of Biochemistry, College of Natural Sciences, Kangwon National University, 192-1 Hyoja-2-dong, Chuncheon, 200-701, Korea, cjlim@kangwon.ac.kr.
Hannah Jo
Kyunghoon Kim
Kangwon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hos3 is involved in cellular growth under osmotic stress in Schizosaccharomyces pombe. The recombinant plasmid pYFHos3 harboring the structural gene encoding Hos3 was constructed. The S. pombe cells harboring pYFHos3 contained the increased hos3 (+) mRNA content and exhibited an enhanced growth in high osmotic conditions, such as 1.5 M KCl and 2.5 M D-glucose, compared with the vector control cells. In the presence of hydrogen peroxide (H2O2), superoxide anion-generating menadione (MD) and nitric oxide (NO)-generating sodium nitroprusside (SNP), they could grow better than the vector control cells. In the presence of H2O2, MD and SNP and in the absence of a nitrogen source, the S. pombe cells harboring pYFHos3 contained less elevated NO and reactive oxygen species (ROS) levels than the vector control cells. Collectively, the S. pombe Hos3 also participate in the cellular defense against oxidative, nitrosative and nutritional stresses through down-regulating ROS and NO levels.

Indexed as

Osmotic PressureOxidative StressStress, PhysiologicalFungal ProteinsMutant ProteinsNitroso CompoundsOxidantsSchizosaccharomycesFungal ProteinsMutant ProteinsNitroso CompoundsOxidants

Identifiers

PMID25342311
OpenAlexW2088112016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.