ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2015
Scatter correction improves concordance in SPECT MPI with a dedicated cardiac SPECT solid-state camera.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Evaluation of modified window-based scatter compensation in quantitativeEJNMMI physics · 2026Article
- Impact of dual-energy window scatter correction on technetium image quality across different energy windows in cadmium-zinc-telluride-based SPECT/CT.EJNMMI physics · 2026Article
- Simultaneous dual-isotope SPECT imaging using a cardiac cadmium-zinc-telluride camera with various Technetium-99 m to Iodine-123 ratios.EJNMMI reports · 2025Article
- A critical phantom study of the energy window used forEJNMMI physics · 2025Article
- Quantitative capabilities of commercial CZT SPECT-CT cameras withEJNMMI physics · 2025Article
- Bias and precision of SPECT-basedEJNMMI physics · 2024Article
- DuDoCFNet: Dual-Domain Coarse-to-Fine Progressive Network for Simultaneous Denoising, Limited-View Reconstruction, and Attenuation Correction of Cardiac SPECT.IEEE transactions on medical imaging · 2024Article
- The Impact of Dual and Triple Energy Window Scatter Correction on I-123 Postsurgical Thyroid SPECT/CT Imaging Using a Phantom with Small Sizes of Thyroid Remnants.Life (Basel, Switzerland) · 2024Article
- Simulation studies of a full-ring, CZT SPECT system for whole-body imaging ofMedical physics · 2023Article
- Evaluation of quantitative accuracy among different scatter corrections for quantitative bone SPECT/CT imaging.PloS one · 2022Article
- Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Noise heterogeneity in attenuation-corrected cardiac SPECT images increases perfusion value uncertainty near the base of the heart.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Experimental evaluation of the GE NM/CT 870 CZT clinical SPECT system equipped with WEHR and MEHRS collimator.Journal of applied clinical medical physics · 2021Article
- The effect of CT-based attenuation correction on the automatic perfusion score of myocardial perfusion imaging using a dedicated cardiac solid-state CZT SPECT/CT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Diagnostic implications of CZT SPECT and impact of CT attenuation correction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Monte Carlo-based quantitative pinhole SPECT reconstruction using a ray-tracing back-projector.EJNMMI physics · 2017Article
- Optimization of a simultaneous dual-isotopeJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCorrection for photon attenuation and scatter improves image quality with conventional NaI-based gamma cameras but evaluation of these corrections for novel solid-state dedicated cardiac cameras is limited. In this study, we assess the accuracy of dual-energy-window (DEW) scatter correction (SC) applied to clinically acquired (99m)Tc-tetrofosmin myocardial perfusion images obtained on a dedicated multi-pinhole camera with cadmium-zinc-telluride (CZT) detectors (GE Discovery NM530) compared to DEW scatter-corrected images from our conventional SPECT camera (GE Infinia Hawkeye 4; INF).
methodsA modified DEW SC method was formulated to account for the detection of primary photons in the lower energy window (120 keV ± 5%) with CZT detectors, in addition to estimating the scattered photons detected in the photopeak window (140 keV ± 10%). Phantom experiments were used to estimate the DEW correction parameters. Data from 108 patients, acquired using a standard rest/stress Tc-99m-tetrofosmin SPECT/CT protocol on both cameras, were reconstructed with no correction (NC), attenuation correction (AC), and AC with DEW-SC. Images were compared based on the summed stress/rest/difference scores (SSS/SRS/SDS) calculated by clinical software.
resultsThe correlation between SSS/SRS for the two cameras was excellent (r ≥ 0.94). The mean difference between cameras was <0.4 for SSS/SRS/SDS scores. Since datasets did not follow a normal distribution, non-parametric tests were used to show significant differences between datasets. Classification of disease (SSS) was highly correlated, as ranked by the two cameras (kendall's tau = 0.72, P < .001). AC significantly reduced the mean difference between the two cameras for SSS/SRS compared to NC. AC without SC on the CZT introduced a bias towards higher scores when compared to the INF, which was reduced after applying SC. Although SC increased noise, the scores for the AC/SC images were not significantly different between the two cameras (P > .1).
conclusionsDEW-SC on the CZT camera was feasible and produced images that are not significantly different from those acquired on the INF camera. Although use of SC on CZT images does increase noise, the resultant noise does not introduce bias relative to the INF camera.
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