Evidence map›Paper›PMID 25342204›Full record

ArticleAmerican journal of epidemiology2014

Negative aspects of close relationships as risk factors for cognitive aging.

Jing Liao, Jenny Head, Meena Kumari, Stephen Stansfeld, Mika Kivimaki, Archana Singh-Manoux, Eric J Brunner

Abstract read
In one paragraph

Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Social support and verbal interaction are differentially associated with cognitive function in midlife and older age.Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition · 2019
    Article
  4. Article
  5. Article
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  10. Structural and functional measures of social relationships and quality of life among older adults: does chronic disease status matter?Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jing Liao
Jenny Head
Meena Kumari
Stephen Stansfeld
Mika Kivimaki
Archana Singh-Manoux
Eric J Brunner

Funding

CHANGES IN HEALTH: SOCIO-ECONOMIC STATUS AND PATHWAYSR37AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G · 1999 to 2008
$4.3M
Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5M
British Heart Foundation RG/13/2/30098Medical Research Council K013351Medical Research Council MR/K013351/1NIA NIH HHS AG13196NIA NIH HHS R01 AG013196NIA NIH HHS R01AG013196NIA NIH HHS R37 AG013196
6 · The paper itself

Abstract

The extent to which social relationships influence cognitive aging is unclear. In this study, we investigated the association of midlife quality of close relationships with subsequent cognitive decline. Participants in the Whitehall II Study (n = 5,873; ages 45-69 years at first cognitive assessment) underwent executive function and memory tests 3 times over a period of 10 years (1997-1999 to 2007-2009). Midlife negative and positive aspects of close relationships were assessed twice using the Close Persons Questionnaire during the 8 years preceding cognitive assessment. Negative aspects of close relationships, but not positive aspects, were associated with accelerated cognitive aging. Participants in the top third of reported negative aspects of close relationships experienced a faster 10-year change in executive function (-0.04 standard deviation, 95% confidence interval: -0.08, -0.01) than those in the bottom third, which was comparable with 1 extra year of cognitive decline for participants aged 60 years after adjustment for sociodemographic and health status. Longitudinal analysis found no evidence of reverse causality. This study highlights the importance of differentiating aspects of social relationships to evaluate their unique associations with cognitive aging.

Indexed as

CognitionSocial EnvironmentAgedAgingFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk Factorsagingcognitive declinelongitudinal studiessocial relationships

Identifiers

PMID25342204
PMCPMC4239796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.