SynthesisAmerican journal of nephrology2014
Body mass index and mortality in kidney transplant recipients: a systematic review and meta-analysis.
Synthesis in American journal of nephrology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Management of obesity in kidney transplant candidates and recipients: A clinical practice guideline by the DESCARTES Working Group of ERA.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2021Guideline
- Association of obesity with mortality and clinical outcomes in children and adolescents with transplantation: A systematic review and meta-analysis.Reviews in endocrine & metabolic disorders · 2021Pooled it
- Exercise training in kidney transplant recipients: a systematic review.Journal of nephrology · 2019Pooled it
- Clinical outcomes of deceased donor kidney transplantation: Eight years of experience from a tertiary care center in India.World journal of nephrology · 2026Article
- Perioperative biomarkers and graft function in living donor kidney transplantation: focus on postoperative prognostic nutritional index.BMC nephrology · 2026Article
- Obesity and Its Clinical Implications in End-Stage Kidney Disease.Medicina (Kaunas, Lithuania) · 2026Review
- Should Kidney Transplantation be Offered to Patients with Body Mass Index >40?: CON.Kidney360 · 2025Article
- Practices in the management of kidney transplant candidates and recipients with obesity: A survey of United States transplant programs.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025Article
- Effects of the pretransplant obesity on kidney transplant outcomes in Korea: a nationwide cohort study.BMC nephrology · 2025Article
- Prognostic Nutritional Index Trajectories Predict Kidney Function in Kidney Transplant Recipients: A Latent Class Growth Model Study.Annals of transplantation · 2025Article
- The Kidney in Obesity: Current Evidence, Perspectives and Controversies.Current obesity reports · 2024Review
- Impact of Recipient and Donor Body Mass Index on Survival Outcomes After Intestinal Transplantation: A United Network for Organ Sharing Database Analysis.Annals of transplantation · 2024Article
- Pica is associated with lower willingness to change negative habits of diet and exercise, inadequate lifestyle, and less healthful food consumption in dialysis.Frontiers in nutrition · 2024Article
- Obesity is Associated With Delayed Graft Function in Kidney Transplant Recipients: A Paired Kidney Analysis.Transplant international : official journal of the European Society for Organ Transplantation · 2023Article
- Obesity and renal disease: Benefits of bariatric surgery.Frontiers in medicine · 2023Review
- Cognitive-behavioral and dietary weight loss intervention in adult kidney transplant recipients with overweight and obesity: Results of a pilot RCT study (Adi-KTx).Frontiers in psychiatry · 2023Article
- Nutrition Disturbances and Metabolic Complications in Kidney Transplant Recipients: Etiology, Methods of Assessment and Prevention-A Review.Nutrients · 2022Review
- Effect of pre and post-transplant body mass index on pediatric kidney transplant outcomes.BMC pediatrics · 2022Article
- Clinical practice guideline exercise and lifestyle in chronic kidney disease.BMC nephrology · 2022Article
- Impact of Size Matching Based on Donor-Recipient Height on Kidney Transplant Outcomes.Transplant international : official journal of the European Society for Organ Transplantation · 2022Observational
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundA higher body mass index (BMI) seems to be linked to survival advantage in maintenance hemodialysis patients. However, it is uncertain if this 'obesity survival paradox' is also observed in kidney transplant recipients. Hence, we systematically reviewed the literature on the impact of pre-transplantation BMI on all-cause mortality in this population.
methodsWe searched MEDLINE, EMBASE, Web of Science, CINAHL, and Cochrane CENTRAL for relevant studies up to July 2013. Two investigators independently selected the studies using predefined criteria, abstracted the data from the included studies, and independently assessed each study's quality using the Newcastle-Ottawa Quality Assessment Scale. In addition to the qualitative synthesis, we quantitatively pooled the results of the studies with clinical, methodological, and statistical homogeneity.
resultsWe screened 7,123 records, from which we included 11 studies (with a total of 305,392 participants) in this systematic review and 4 studies in the meta-analyses. In the only study that included children, obesity was linked to higher mortality in children of 6-12 years old. For adults, our meta-analyses indicated that compared to normal BMI, underweight [Hazard Ratio (HR): 1.09; 95% Confidence Interval (CI): 1.02-1.20], overweight (HR: 1.07; 95% CI: 1.04-1.12), and obese (HR: 1.20; 95% CI: 1.14-1.23) levels of BMI were associated with higher mortality.
conclusionThe presence of the obesity survival paradox is unlikely in kidney transplant recipients since both extremes of pre-transplantation BMI are linked to higher mortality in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.