ArticleToxins2014
Aflatoxin B₁ degradation by a Pseudomonas strain.
Article in Toxins, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed, 132 citations in OpenAlex.
- Biodegradation of Aflatoxins by Four Novel Environmental Bacterial Isolates: A Comparative Genomic and Molecular Docking-Proof-of-Concept Study.Foods (Basel, Switzerland) · 2026Article
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- Article
- Intestinal Microecological Mechanisms of Aflatoxin B1 Degradation by Black Soldier Fly Larvae (Animals : an open access journal from MDPI · 2025Review
- Bentonite clay in aflatoxin mitigation: advances, efficiency and perspectives.Archives of microbiology · 2025Review
- Study on the Enrichment of the Main Active Components inFoods (Basel, Switzerland) · 2025Article
- Self-Sufficient Aflatoxin Decontamination System: MOF-Based Composite Membrane with Peroxidase-Mimic and Controlled HToxins · 2025Article
- A Review of Research Progress on the Microbial or Enzymatic Degradation and Mechanism of Aflatoxin B1.Journal of microbiology and biotechnology · 2025Review
- Starch can expedite the screening for bacterial aflatoxin degraders.Scientific reports · 2024Article
- A novel enrofloxacin-degrading fungus, Humicola sp. KC0924g, isolated from the rhizosphere sediment of the submerged macrophyte Vallisneria spiralis L.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Enzymatic Oxidation of Aflatoxin MFoods (Basel, Switzerland) · 2024Article
- Negative Effects of Occurrence of Mycotoxins in Animal Feed and Biological Methods of Their Detoxification: A Review.Molecules (Basel, Switzerland) · 2024Review
- Aflatoxin B1 Control by VariousToxins · 2024Article
- Identification of a Novel Aflatoxin BToxins · 2024Article
- Contamination and Control of Mycotoxins in Grain and Oil Crops.Microorganisms · 2024Review
- Tuning Thermostability and Catalytic Efficiency of Aflatoxin-Degrading Enzyme by Error-prone PCR.Applied microbiology and biotechnology · 2023Article
- Mycotoxin Contamination Status of Cereals in China and Potential Microbial Decontamination Methods.Metabolites · 2023Review
- Degradation of Aflatoxin BFoods (Basel, Switzerland) · 2023Article
- Characteristics of Aflatoxin BLife (Basel, Switzerland) · 2023Article
- Biodegradation of Aflatoxin BToxins · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aflatoxin B1 (AFB1), one of the most potent naturally occurring mutagens and carcinogens, causes significant threats to the food industry and animal production. In this study, 25 bacteria isolates were collected from grain kernels and soils displaying AFB1 reduction activity. Based on its degradation effectiveness, isolate N17-1 was selected for further characterization and identified as Pseudomonas aeruginosa. P. aeruginosa N17-1 could degrade AFB₁, AFB₂ and AFM₁ by 82.8%, 46.8% and 31.9% after incubation in Nutrient Broth (NB) medium at 37 °C for 72 h, respectively. The culture supernatant of isolate N17-1 degraded AFB₁ effectively, whereas the viable cells and intra cell extracts were far less effective. Factors influencing AFB1 degradation by the culture supernatant were investigated. Maximum degradation was observed at 55 °C. Ions Mn²⁺ and Cu²⁺ were activators for AFB1 degradation, however, ions Mg²⁺, Li⁺, Zn²⁺, Se²⁺, Fe³⁺ were strong inhibitors. Treatments with proteinase K and proteinase K plus SDS significantly reduced the degradation activity of the culture supernatant. No degradation products were observed based on preliminary LC-QTOF/MS analysis, indicating AFB₁ was metabolized to degradation products with chemical properties different from that of AFB₁. The results indicated that the degradation of AFB₁ by P. aeruginosa N17-1 was enzymatic and could have a great potential in industrial applications. This is the first report indicating that the isolate of P. aeruginosa possesses the ability to degrade aflatoxin.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.