Evidence map›Paper›PMID 25341381›Full record

ArticleCritical care (London, England)2014

Multi-scale symbolic entropy analysis provides prognostic prediction in patients receiving extracorporeal life support.

Yen-Hung Lin, Hui-Chun Huang, Yi-Chung Chang, Chen Lin, Men-Tzung Lo, Li-Yu Daisy Liu, Pi-Ru Tsai, Yih-Sharng Chen, Wen-Je Ko, Yi-Lwun Ho and 3 more

Open access · goldAbstract read
In one paragraph

Article in Critical care (London, England), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 41 citations in OpenAlex.

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  5. [Investigation on new paradigm of clinical physiological monitoring by using wearable devices].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Yen-Hung LinDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. austinr34@gmail.com.
Hui-Chun HuangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. hchuangster@ntuh.gov.tw.
Yi-Chung ChangGraduate Institute of Communication Engineering, National Taiwan University, Taipei, Taiwan. tako0215@hotmail.com.
Chen LinResearch Center for Adaptive Data Analysis, National Central University, No. 300, Jhongda Rd, Taoyuan County, 32001, Taiwan. dreamtheater.lin@gmail.com.
Men-Tzung LoResearch Center for Adaptive Data Analysis, National Central University, No. 300, Jhongda Rd, Taoyuan County, 32001, Taiwan. mzlo@ncu.edu.tw.
Li-Yu Daisy LiuDepartment of Agronomy, Biometry Division, National Taiwan University, Taipei, Taiwan. lyliu@ntu.edu.tw.
Pi-Ru TsaiDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. pirutsai@yahoo.com.tw.
Yih-Sharng ChenDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. yschen1234@gmail.com.
Wen-Je KoDepartment of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. kowj@ntu.edu.tw.
Yi-Lwun HoDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. ylho@ntu.edu.tw.
Ming-Fong ChenDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan. mfchen@ntuh.gov.tw.
Chung-Kang PengResearch Center for Adaptive Data Analysis, National Central University, No. 300, Jhongda Rd, Taoyuan County, 32001, Taiwan. ckpeng@comcast.net.
Timothy G BuchmanDepartment of Surgery, Emory University School of Medicine, Atlanta, Georgia, USA. tbuchma@emory.edu.
National Taiwan University Hospital · TWNational Central University · TWNational Taiwan University · TWEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExtracorporeal life support (ECLS) can temporarily support cardiopulmonary function, and is occasionally used in resuscitation. Multi-scale entropy (MSE) derived from heart rate variability (HRV) is a powerful tool in outcome prediction of patients with cardiovascular diseases. Multi-scale symbolic entropy analysis (MSsE), a new method derived from MSE, mitigates the effect of arrhythmia on analysis. The objective is to evaluate the prognostic value of MSsE in patients receiving ECLS. The primary outcome is death or urgent transplantation during the index admission.

methodsFifty-seven patients receiving ECLS less than 24 hours and 23 control subjects were enrolled. Digital 24-hour Holter electrocardiograms were recorded and three MSsE parameters (slope 5, Area 6-20, Area 6-40) associated with the multiscale correlation and complexity of heart beat fluctuation were calculated.

resultsPatients receiving ECLS had significantly lower value of slope 5, area 6 to 20, and area 6 to 40 than control subjects. During the follow-up period, 29 patients met primary outcome. Age, slope 5, Area 6 to 20, Area 6 to 40, acute physiology and chronic health evaluation II score, multiple organ dysfunction score (MODS), logistic organ dysfunction score (LODS), and myocardial infarction history were significantly associated with primary outcome. Slope 5 showed the greatest discriminatory power. In a net reclassification improvement model, slope 5 significantly improved the predictive power of LODS; Area 6 to 20 and Area 6 to 40 significantly improved the predictive power in MODS. In an integrated discrimination improvement model, slope 5 added significantly to the prediction power of each clinical parameter. Area 6 to 20 and Area 6 to 40 significantly improved the predictive power in sequential organ failure assessment.

conclusionsMSsE provides additional prognostic information in patients receiving ECLS.

Indexed as

EntropyLife Support SystemsAdultAgedExtracorporeal CirculationFemaleHeart RateHumansMaleMiddle AgedPredictive Value of TestsPrognosisProspective Studies

Identifiers

PMID25341381
PMCPMC4221713
OpenAlexW2106835861

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.