Evidence map›Paper›PMID 25341132›Full record

ReviewAJR. American journal of roentgenology2014

Imaging-based screening: understanding the controversies.

Diana L Lam, Pari V Pandharipande, Janie M Lee, Constance D Lehman, Christoph I Lee

Registry-linked trialAbstract readReview
In one paragraph

Review in AJR. American journal of roentgenology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06391749 (K-ACCELERATE), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06391749 enrolling by invitationnot on this mapstarted 2024, after this paper: background citation

K-ACCELERATE: A Multi-center Prospective Trial to Evaluate Clinical Utility of Multi Cancer Early Detection Test as a Triage Test for Symptomatic Participants

TypeobservationalSponsorGene SolutionsRan2024 to 2026Enrolled1,000ConditionsCancer Colon, Cancer, Liver, Cancer, Lung, Cancer, Breast
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Towards optimized CT lung cancer screening scan protocols.The British journal of radiology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Abdominal aortic aneurysm screening: concepts and controversies.Cardiovascular diagnosis and therapy · 2018
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diana L Lam1 Department of Radiology, University of Washington School of Medicine, 825 Eastlake Ave E, G3-200, Seattle, WA 98109-1023.
Pari V Pandharipande
Janie M Lee
Constance D Lehman
Christoph I Lee

Funding

Cost-Effectiveness of Radiofrequency Ablation for Small, Incidental Renal TumorsK07CA133097 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI PANDHARIPANDE, PARI VIJAY · 2009 to 2013
$891k
NCI NIH HHS K07 CA133097NCI NIH HHS K07CA133097
6 · The paper itself

Abstract

objectiveThe goals of this article are to provide an overview of controversial aspects of imaging-based screening and to elucidate potential risks that may offset anticipated benefits.

conclusionCurrent controversial topics associated with imaging-based screening include false-positive results, incidental findings, overdiagnosis, radiation risks, and costs. Alongside the benefits of screening, radiologists should be prepared to discuss these additional diagnostic consequences with providers and patients to better guide shared decision making regarding imaging-based screening.

Indexed as

Diagnostic ImagingEarly Detection of CancerHealth Services MisuseHumansNeoplasmsReproducibility of ResultsRisk AssessmentSensitivity and Specificityfalse-positiveincidental findingsoverdiagnosisscreening

Identifiers

PMID25341132
PMCPMC4220242

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.