ArticlePloS one2014
Resistance training improves hemodynamic function, collagen deposition and inflammatory profiles: experimental model of heart failure.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Trial
- Aerobic exercise reduces oxidative damage and improves heart function in diabetic rats with heart failure: No extra effect from photobiomodulation.Journal of diabetes and metabolic disorders · 2026Article
- FNDC5/Irisin-dependent renoprotection of resistance training in myocardial infarction-induced Type 2 cardiorenal syndrome.PloS one · 2026Article
- Animal Models of Exercise From Rodents to Pythons.Circulation research · 2022Review
- Unveiling the role of exercise training in targeting the inflammatory paradigm of heart failure with preserved ejection fraction: a narrative review.Heart failure reviews · 2022Review
- Preventive training does not interfere with mRNA-encoding myosin and collagen expression during pulmonary arterial hypertension.PloS one · 2021Article
- Resistance training affects the hemodynamic parameters of hypertensive and normotensive women differently, and regardless of performance improvement.Journal of exercise science and fitness · 2020Article
- Impacts of exercise intervention on various diseases in rats.Journal of sport and health science · 2020Review
- Quantification of DNA Damage in Different Tissues in Rats with Heart Failure.Arquivos brasileiros de cardiologia · 2020Article
- Resistance training promotes reduction in Visceral Adiposity without improvements in Cardiomyocyte Contractility and Calcium handling in Obese Rats.International journal of medical sciences · 2020Article
- Cardioprotective Effects of Resistance Training on Obesity.Arquivos brasileiros de cardiologia · 2019Article
- [Effect of long-term resistance exercise on masseter muscle mechanical hyperalgesia in rats].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2019Article
- Effect of Resistance Training on Extracellular Matrix Adaptations in Skeletal Muscle of Older Rats.Frontiers in physiology · 2018Article
- Cardiovascular Adaptations Induced by Resistance Training in Animal Models.International journal of medical sciences · 2018Review
- Resistance training attenuates salt overload-induced cardiac remodeling and diastolic dysfunction in normotensive rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2017Article
- Enhancement of Skeletal Muscle in Aged Rats Following High-Intensity Stretch-Shortening Contraction Training.Rejuvenation research · 2017Article
- Strength training prior to muscle injury potentiates low-level laser therapy (LLLT)-induced muscle regeneration.Lasers in medical science · 2017Article
- Maximal oxygen uptake and exercise tolerance are improved in rats with heart failure subjected to low-level laser therapy associated with resistance training.Lasers in medical science · 2017Article
- High-intensity resistance training alone or combined with aerobic training improves strength, heart function and collagen in rats with heart failure.American journal of translational research · 2017Article
- Light-emitting diode therapy (LEDT) improves functional capacity in rats with heart failure.Lasers in medical science · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The role of resistance training on collagen deposition, the inflammatory profile and muscle weakness in heart failure remains unclear. Therefore, this study evaluated the influence of a resistance training program on hemodynamic function, maximum strength gain, collagen deposition and inflammatory profile in chronic heart failure rats. Thirty-two male Wistar rats submitted to myocardial infarction by coronary artery ligation or sham surgery were assigned into four groups: sedentary sham (S-Sham, n = 8); trained sham (T-Sham, n = 8); sedentary chronic heart failure (S-CHF, n = 8) and trained chronic heart failure (T-CHF, n = 8). The maximum strength capacity was evaluated by the one maximum repetition test. Trained groups were submitted to an 8-week resistance training program (4 days/week, 4 sets of 10-12 repetitions/session, at 65% to 75% of one maximum repetition). After 8 weeks of the resistance training program, the T-CHF group showed lower left ventricular end diastolic pressure (P<0.001), higher left ventricular systolic pressure (P<0.05), higher systolic blood pressure (P<0.05), an improvement in the maximal positive derivative of ventricular pressure (P<0.05) and maximal negative derivative of ventricular pressure (P<0.05) when compared to the S-CHF group; no differences were observed when compared to Sham groups. In addition, resistance training was able to reduce myocardial hypertrophy (P<0.05), left ventricular total collagen volume fraction (P<0.01), IL-6 (P<0.05), and TNF-α/IL-10 ratio (P<0.05), as well as increasing IL-10 (P<0.05) in chronic heart failure rats when compared to the S-CHF group. Eight weeks of resistance training promotes an improvement of cardiac function, strength gain, collagen deposition and inflammatory profile in chronic heart failure rats.
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