ReviewNutrients2014
Animal models of compulsive eating behavior.
Review in Nutrients, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 45 citations in OpenAlex.
- Addictive-like behavioural traits in pet dogs with extreme motivation for toy play.Scientific reports · 2025Article
- Evidence for food-related and non-food-related maladaptive preference in a mouse model of binge eating disorder.Frontiers in behavioral neuroscience · 2025Article
- Current perspectives on brain circuits involved in food addiction-like behaviors.Journal of neural transmission (Vienna, Austria : 1996) · 2024Review
- The Neurobiology of Eating Behavior in Obesity: Mechanisms and Therapeutic Targets: A Report from the 23rd Annual Harvard Nutrition Obesity Symposium.The American journal of clinical nutrition · 2023Article
- Non-human contributions to personality neuroscience - from fish through primates. An introduction to the special issue.Personality neuroscience · 2022Review
- Adaptive Changes in the Central Control of Energy Homeostasis Occur in Response to Variations in Energy Status.International journal of molecular sciences · 2021Review
- Emotional Regulation and Overeating Behaviors in Children and Adolescents: A Systematic Review.Behavioral sciences (Basel, Switzerland) · 2021Review
- Random access to palatable food stimulates similar addiction-like responses as a fixed schedule, but only a fixed schedule elicits anticipatory activation.Scientific reports · 2019Article
- Protocol for Measuring Compulsive-like Feeding Behavior in Mice.Bio-protocol · 2019Article
- Chronic stress increases susceptibility to food addiction by increasing the levels of DR2 and MOR in the nucleus accumbens.Neuropsychiatric disease and treatment · 2019Article
- Review
- Prevalence of food addiction among Iranian children and adolescents: Associations with sociodemographic and anthropometric indices.Medical journal of the Islamic Republic of Iran · 2018Article
- Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0) and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants.Frontiers in psychiatry · 2018Article
- Pathological Overeating: Emerging Evidence for a Compulsivity Construct.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2017Review
- Emotional Eating, Binge Eating and Animal Models of Binge-Type Eating Disorders.Current obesity reports · 2017Review
- Food Addiction in Gambling Disorder: Frequency and Clinical Outcomes.Frontiers in psychology · 2017Article
- Rewarding Effects of Operant Dry-Licking Behavior on Neuronal Firing in the Nucleus Accumbens Core.Frontiers in pharmacology · 2017Article
- Similarities between obesity in pets and children: the addiction model.The British journal of nutrition · 2016Article
- Differential Gambling Motivations and Recreational Activity Preferences Among Casino Gamblers.Journal of gambling studies · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eating disorders are multifactorial conditions that can involve a combination of genetic, metabolic, environmental, and behavioral factors. Studies in humans and laboratory animals show that eating can also be regulated by factors unrelated to metabolic control. Several studies suggest a link between stress, access to highly palatable food, and eating disorders. Eating "comfort foods" in response to a negative emotional state, for example, suggests that some individuals overeat to self-medicate. Clinical data suggest that some individuals may develop addiction-like behaviors from consuming palatable foods. Based on this observation, "food addiction" has emerged as an area of intense scientific research. A growing body of evidence suggests that some aspects of food addiction, such as compulsive eating behavior, can be modeled in animals. Moreover, several areas of the brain, including various neurotransmitter systems, are involved in the reinforcement effects of both food and drugs, suggesting that natural and pharmacological stimuli activate similar neural systems. In addition, several recent studies have identified a putative connection between neural circuits activated in the seeking and intake of both palatable food and drugs. The development of well-characterized animal models will increase our understanding of the etiological factors of food addiction and will help identify the neural substrates involved in eating disorders such as compulsive overeating. Such models will facilitate the development and validation of targeted pharmacological therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.