ReviewExpert review of cardiovascular therapy2014
Making it stick: chasing the optimal stem cells for cardiac regeneration.
Review in Expert review of cardiovascular therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Harnessing stem cell and lineage reprogramming technology to treat cardiac fibrosis.Cell regeneration (London, England) · 2023Review
- Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes.Stem cell research & therapy · 2018Article
- Enhancement Strategies for Cardiac Regenerative Cell Therapy: Focus on Adult Stem Cells.Circulation research · 2018Review
- Recent Advances in Treatment of Coronary Artery Disease: Role of Science and Technology.International journal of molecular sciences · 2018Review
- Bmi1 and BRG1 drive myocardial repair by regulating cardiac stem cell function in acute rheumatic heart disease.Experimental and therapeutic medicine · 2017Article
- Myocardial Reparative Properties of Cardiac Mesenchymal Cells Isolated on the Basis of Adherence.Journal of the American College of Cardiology · 2017Article
- The Elusive Progenitor Cell in Cardiac Regeneration: Slip Slidin' Away.Circulation research · 2017Review
- Nanowires and Electrical Stimulation Synergistically Improve Functions of hiPSC Cardiac Spheroids.Nano letters · 2016Article
- Unique Features of Cortical Bone Stem Cells Associated With Repair of the Injured Heart.Circulation research · 2015Article
- Cardiac Stem Cell Hybrids Enhance Myocardial Repair.Circulation research · 2015Article
- Activation of Notch1 signalling promotes multi-lineage differentiation of c-Kit(POS)/NKX2.5(POS) bone marrow stem cells: implication in stem cell translational medicine.Stem cell research & therapy · 2015Article
- Notch activation enhances lineage commitment and protective signaling in cardiac progenitor cells.Basic research in cardiology · 2015Article
- Rejuvenating the senescent heart.Current opinion in cardiology · 2015Review
- Generating primary cultures of murine cardiac myocytes and cardiac fibroblasts to study viral myocarditis.Methods in molecular biology (Clifton, N.J.) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Despite the increasing use of stem cells for regenerative-based cardiac therapy, the optimal stem cell population(s) remains in a cloud of uncertainty. In the past decade, the field has witnessed a surge of researchers discovering stem cell populations reported to directly and/or indirectly contribute to cardiac regeneration through processes of cardiomyogenic commitment and/or release of cardioprotective paracrine factors. This review centers upon defining basic biological characteristics of stem cells used for sustaining cardiac integrity during disease and maintenance of communication between the cardiac environment and stem cells. Given the limited successes achieved so far in regenerative therapy, the future requires development of unprecedented concepts involving combinatorial approaches to create and deliver the optimal stem cell(s) that will enhance myocardial healing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.