Evidence map›Paper›PMID 25340049›Full record

ReviewFrontiers in chemistry2014

Exopolysaccharides produced by marine bacteria and their applications as glycosaminoglycan-like molecules.

Christine Delbarre-Ladrat, Corinne Sinquin, Lou Lebellenger, Agata Zykwinska, Sylvia Colliec-Jouault

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in chemistry, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
18.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 128 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christine Delbarre-LadratEM3B Laboratory, Institut Français de Recherche pour l'Exploitation de la Mer Nantes, France.
Corinne SinquinEM3B Laboratory, Institut Français de Recherche pour l'Exploitation de la Mer Nantes, France.
Lou LebellengerEM3B Laboratory, Institut Français de Recherche pour l'Exploitation de la Mer Nantes, France.
Agata ZykwinskaEM3B Laboratory, Institut Français de Recherche pour l'Exploitation de la Mer Nantes, France.
Sylvia Colliec-JouaultEM3B Laboratory, Institut Français de Recherche pour l'Exploitation de la Mer Nantes, France.
Institut Français · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although polysaccharides are ubiquitous and the most abundant renewable bio-components, their studies, covered by the glycochemistry and glycobiology fields, remain a challenge due to their high molecular diversity and complexity. Polysaccharides are industrially used in food products; human therapeutics fall into a more recent research field and pharmaceutical industry is looking for more and more molecules with enhanced activities. Glycosaminoglycans (GAGs) found in animal tissues play a critical role in cellular physiological and pathological processes as they bind many cellular components. Therefore, they present a great potential for the design and preparation of therapeutic drugs. On the other hand, microorganisms producing exopolysaccharides (EPS) are renewable resources meeting well the actual industrial demand. In particular, the diversity of marine microorganisms is still largely unexplored offering great opportunities to discover high value products such as new molecules and biocatalysts. EPS-producing bacteria from the marine environment will be reviewed with a focus on marine-derived EPS from bacteria isolated from deep-sea hydrothermal vents. Information on chemical and structural features, putative pathways of biosynthesis, novel strategies for chemical and enzymatic modifications and potentialities in the biomedical field will be provided. An integrated approach should be used to increase the basic knowledge on these compounds and their applications; new clean environmentally friendly processes for the production of carbohydrate bioactive compounds should also be proposed for a sustainable industry.

Indexed as

biodiversitybiological activitybiosynthesisGAG-mimeticmarine-derived polysaccharidemodificationstructure

Identifiers

PMID25340049
PMCPMC4189415
OpenAlexW2122272312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.