ArticleFrontiers in oncology2014
Stereotactic body radiotherapy as primary therapy for head and neck cancer in the elderly or patients with poor performance.
Article in Frontiers in oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- [New developments in the radiotherapy for head and neck cancer].Magyar onkologia · 2025Review
- Response of Spontaneous Oral Tumors in Canine Cancer Patients Treated with Stereotactic Body Radiation Therapy (SBRT).Radiation research · 2024Article
- Stereotactic ablative radiotherapy for treating primary head and neck cancer and locoregional recurrence: A comprehensive review of the literature.Clinical and translational radiation oncology · 2024Article
- The Evolving Role of Stereotactic Body Radiation Therapy for Head and Neck Cancer: Where Do We Stand?Cancers · 2023Review
- Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers.Molecules (Basel, Switzerland) · 2023Article
- The immunogenic radiation and new players in immunotherapy and targeted therapy for head and neck cancer.Frontiers in oral health · 2023Review
- Prediction of Radiotherapy Compliance in Elderly Cancer Patients Using an Internally Validated Decision Tree.Cancers · 2022Article
- Canine oral squamous cell carcinoma as a spontaneous, translational model for radiation and immunology research.Frontiers in oncology · 2022Article
- Efficacy Analysis of Separation Surgery Combined with SBRT for Spinal Metastases-A Long-Term Follow-Up Study Based on Patients with Spinal Metastatic Tumor in a Single-Center.Orthopaedic surgery · 2020Article
- Managing an Older Adult with Cancer: Considerations for Radiation Oncologists.BioMed research international · 2017Review
- Stereotactic body radiotherapy for the pancreas: a critical review for the medical oncologist.Journal of gastrointestinal oncology · 2016Review
- Treatment of Elderly Patients with Squamous Cell Carcinoma of the Head and Neck.Frontiers in oncology · 2016Review
- Stereotactic Radiation Therapy for De Novo Head and Neck Cancers: A Systematic Review and Meta-Analysis.Advances in radiation oncologyArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveStereotactic body radiotherapy (SBRT) is increasingly used to treat a variety of tumors, including head and neck squamous cell carcinoma (HNSCC) in the recurrent setting. While there are published data for re-irradiation using SBRT for HNSCC, there are limited data supporting its use as upfront treatment for locally advanced disease. STUDY DESIGN/
methodsHere, we describe three patients who received SBRT as the primary treatment for their HNSCC along with a review of the current literature and discussion of future pathways.
resultsThe three cases discussed tolerated treatment well with manageable acute toxicities and had either a clinical or radiographic complete response to therapy.
conclusionHead and neck squamous cell carcinoma presents a unique challenge in the elderly, where medical comorbidities make it difficult to tolerate conventional radiation, often given with a systemic sensitizer. For these individuals, providing a shortened course using SBRT may offer an effective alternative.
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