Evidence map›Paper›PMID 25339954›Full record

ReviewFrontiers in immunology2014

"Of mice and men": arginine metabolism in macrophages.

Anita C Thomas, Joshua T Mattila

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed, 163 citations in OpenAlex.

  1. Article
  2. Article
  3. Nutrients · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Dissecting inflammation in the immunemetabolomic era.Cellular and molecular life sciences : CMLS · 2025
    Review
  15. The roles of arginases and arginine in immunity.Nature reviews. Immunology · 2025
    Review
  16. Macrophage energy metabolism in cardiometabolic disease.Molecular and cellular biochemistry · 2025
    Review
  17. Article
  18. Review
  19. Article
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Anita C ThomasBristol Heart Institute, School of Clinical Sciences, University of Bristol , Bristol , UK.
Joshua T MattilaDepartment of Microbiology and Molecular Genetics, University of Pittsburgh , Pittsburgh, PA , USA.
NIHR Bristol Cardiovascular Biomedical Research Unit · GBUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

arginasehuman macrophagemacrophage activationmacrophage polarizationnitric oxide synthase

Identifiers

PMID25339954
PMCPMC4188127
OpenAlexW2096496652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.