ArticleFrontiers in aging neuroscience2014
KIBRA gene polymorphism has no association with verbal or visual episodic memory performance.
Article in Frontiers in aging neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- KIBRA single nucleotide polymorphism is associated with hippocampal subfield volumes and cognition across development.Brain structure & function · 2024Article
- Thalamic gray matter volume mediates the association between KIBRA polymorphism and olfactory function among older adults: a population-based study.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- KIBRA T allele influences memory performance and progression of cognitive decline: a 7-year follow-up study in subjective cognitive decline and mild cognitive impairment.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Article
- KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden.Scientific reports · 2018Article
- Article
- Age-Modulated Associations betweenFrontiers in aging neuroscience · 2017Article
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Authors and funding
3 authors.
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Abstract
Inter-individual variability in memory performance has been suggested to result, in part, from genetic differences in the coding of proteins involved in long-term potentiation (LTP). The present study examined the effect of a single-nucleotide polymorphism (SNP) in the KIBRA gene (rs17070145) on episodic memory performance, using multiple measures of verbal and visual episodic memory. A total of 256 female and 130 male healthy, older adults (mean age = 60.86 years) were recruited from the Tasmanian Healthy Brain Project (THBP), undergoing both neuropsychological and genetic testing. The current study showed no significant effect of the KIBRA polymorphism on performance on the Rey Auditory Verbal Learning Task, Logical Memory test, Paired Associates Learning test or Rey Complex Figure Task. The results suggest there is little to no functional significance of KIBRA genotype on episodic memory performance, regardless of modality.
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