ReviewWorld journal of gastroenterology2014
Laparoscopic fundoplication for gastroesophageal reflux disease.
Review in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05238636 (The Effect of Anti-reflux Procedures), which is not on this map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Anti-reflux Procedures (Stretta, LINX, and Fundoplication) on Physiological Parameters Contributing to Symptom Resolution in Adults With Gastro-oesophageal Reflux at a Single UK Tertiary Centre
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Transthoracic fundoplication using the Belsey Mark IV technique versus Nissen fundoplication: A systematic review and meta-analysis.Surgical endoscopy · 2023Pooled it
- Evaluation of ICARUS Guidelines and Recommendations Not Supported by Randomized Controlled Trials.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Pooled it
- Application of multi-perspective nursing based on the whole-course ERAS concept during laparoscopic fundoplication in patients with PPI-dependent gastroesophageal reflux disease.African health sciences · 2025Trial
- New treatment method for refractory gastroesophageal reflux disease (GERD): C-BLART (clip band ligation anti-reflux therapy)-a short-term study.Surgical endoscopy · 2020Trial
- Perioperative morbidity and midterm outcomes following antireflux surgery in overweight and obese populations.Surgical endoscopy · 2026Article
- Comparing Nissen, Toupet, Dor, His reconstruction, and W-H fundoplication: real-world 1-year outcomes of five laparoscopic antireflux procedures.Surgical endoscopy · 2026Article
- Correlation between oral microbiome characteristics and clinical phenotypes in patients with GERD and its changes after anti-reflux surgery.Frontiers in microbiology · 2026Article
- Preoperative sarcopenia and its impact on postoperative complications in laparoscopic anti-reflux surgery: a clinical analysis.Frontiers in surgery · 2026Article
- Evaluating the long-term efficacy of robotic anti-reflux surgery on symptom resolution in gerd patients: a comprehensive analysis of typical and atypical presentations.Surgical endoscopy · 2025Article
- Review
- 3D mesh-augmented hiatal hernia repair in patients with GERD: A 3-year single-center experience.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Clinical characteristics and risk factors of esophageal reflux hypersensitivity: A multicenter study.World journal of gastroenterology · 2025Article
- Article
- Comparative efficacy of laparoscopic Dor and Nissen fundoplication for refractory gastroesophageal reflux disease.American journal of translational research · 2025Article
- Laparoscopic Hiatal Hernia Repair: Short-Term Results From Yemen in a Resource-Limited Setting.Cureus · 2025Article
- Fundoplication for Pediatric Gastroesophageal Reflux Disease: Indications, Techniques, and Outcomes.Cureus · 2024Article
- Endoscopic assessment of failed fundoplications differs between endoscopists.Surgical endoscopy · 2024Article
- Long-term disease-specific quality of life after laparoscopic Nissen fundoplication in patients with borderline GERD.Surgical endoscopy · 2024Article
- Current Trends in the Management of Hiatal Hernia: A Literature Review of 10 Years of Data.Cureus · 2024Review
- Acute gastric volvulus complicated by gastric perforation following laparoscopic Nissen fundoplication; A case report.International journal of surgery case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux disease (GERD) is a condition that develops when the reflux of gastric contents into the esophagus leads to troublesome symptoms and/or complications. Heartburn is the cardinal symptom, often associated with regurgitation. In patients with endoscopy-negative heartburn refractory to proton pump inhibitor (PPI) therapy and when the diagnosis of GERD is in question, direct reflux testing by impedance-pH monitoring is warranted. Laparoscopic fundoplication is the standard surgical treatment for GERD. It is highly effective in curing GERD with a 80% success rate at 20-year follow-up. The Nissen fundoplication, consisting of a total (360°) wrap, is the most commonly performed antireflux operation. To reduce postoperative dysphagia and gas bloating, partial fundoplications are also used, including the posterior (Toupet) fundoplication, and the anterior (Dor) fundoplication. Currently, there is consensus to advise laparoscopic fundoplication in PPI-responsive GERD only for those patients who develop untoward side-effects or complications from PPI therapy. PPI resistance is the real challenge in GERD. There is consensus that carefully selected GERD patients refractory to PPI therapy are eligible for laparoscopic fundoplication, provided that objective evidence of reflux as the cause of ongoing symptoms has been obtained. For this purpose, impedance-pH monitoring is regarded as the diagnostic gold standard.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.