Trial reportThe Journal of neuroscience : the official journal of the Society for Neuroscience2014
Medial temporal lobe coding of item and spatial information during relational binding in working memory.
Trial report in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed.
- Acute Hyperglycemia and Spatial Working Memory in Adolescents With Type 1 Diabetes.Diabetes care · 2020Trial
- Article
- The Orbitofrontal Cortex Represents the Allocentric Spatial States of Dynamic Agents Within a Static Environmental Framework.Neuroscience bulletin · 2026Article
- Neural mechanisms of feature binding in working memory.Communications biology · 2026Article
- The role of spatial processing in verbal serial order working memory.Cognitive, affective & behavioral neuroscience · 2025Article
- Neural network models of autonomous adaptive intelligence and artificial general intelligence: how our brains learn large language models and their meanings.Frontiers in systems neuroscience · 2025Article
- Persistent activity during working memory maintenance predicts long-term memory formation in the human hippocampus.Neuron · 2024Article
- Article
- High frequency post-pause word choices and task-dependent speech behavior characterize connected speech in individuals with mild cognitive impairment.medRxiv : the preprint server for health sciences · 2024Article
- Persistent activity during working memory maintenance predicts long-term memory formation in the human hippocampus.bioRxiv : the preprint server for biology · 2024Article
- The medial temporal lobe supports the quality of visual short-term memory representation.Nature human behaviour · 2023Article
- Article
- Article
- Inverse forgetting in unconscious episodic memory.Scientific reports · 2022Article
- Altruism under Stress: Cortisol Negatively Predicts Charitable Giving and Neural Value Representations Depending on Mentalizing Capacity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Evidence for a gradient within the medial temporal lobes for flexible retrieval under hierarchical task rules.Hippocampus · 2021Article
- Article
- Prefrontal lesions disrupt oscillatory signatures of spatiotemporal integration in working memory.Cortex; a journal devoted to the study of the nervous system and behavior · 2021Article
- Non-linear Functional Brain Co-activations in Short-Term Memory Distortion Tasks.Frontiers in neuroscience · 2021Article
- Reunification of Object and View-Center Background Information in the Primate Medial Temporal Lobe.Frontiers in behavioral neuroscience · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Several models have proposed that different medial temporal lobe (MTL) regions represent different kinds of information in the service of long-term memory. For instance, it has been proposed that perirhinal cortex (PRC), parahippocampal cortex (PHC), and hippocampus differentially support long-term memory for item information, spatial context, and item-context relations present during an event, respectively. Recent evidence has indicated that, in addition to long-term memory, MTL subregions may similarly contribute to processes that support the retention of complex spatial arrangements of objects across short delays. Here, we used functional magnetic resonance imaging and multivoxel pattern similarity analysis to investigate the extent to which human MTL regions independently code for object and spatial information, as well as the conjunction of this information, during working memory encoding and active maintenance. Voxel activity patterns in PRC, temporopolar cortex, and amygdala carried information about individual objects, whereas activity patterns in the PHC and posterior hippocampus carried information about the configuration of spatial locations that was to be remembered. Additionally, the integrity of multivoxel patterns in the right anterior hippocampus across encoding and delay periods was predictive of accurate short-term memory for object-location relationships. These results are consistent with parallel processing of item and spatial context information by PRC and PHC, respectively, and the binding of item and context by the hippocampus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.