ArticleProceedings. Biological sciences2014
Multidimensionality in host manipulation mimicked by serotonin injection.
Article in Proceedings. Biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 50 citations in OpenAlex.
- Laser-based selective killing of a manipulative parasite reveals partial reversibility of phenotypic alterations in its intermediate host.Current research in parasitology & vector-borne diseases · 2024Article
- Adaptive host responses to infection can resemble parasitic manipulation.Ecology and evolution · 2023Article
- Article
- Hooking the scientific community on thorny-headed worms: interesting and exciting facts, knowledge gaps and perspectives for research directions on Acanthocephala.Parasite (Paris, France) · 2023Article
- Infection with an acanthocephalan helminth reduces anxiety-like behaviour in crustacean host.Scientific reports · 2022Article
- Host behaviour alteration by its parasite: from brain gene expression to functional test.Proceedings. Biological sciences · 2020Article
- Warming can alter host behavior in a similar manner to infection with behavior-manipulating parasites.Oecologia · 2020Article
- Increased temperature has no consequence for behavioral manipulation despite effects on both partners in the interaction between a crustacean host and a manipulative parasite.Scientific reports · 2020Article
- Brain-encysting trematodes (Biology open · 2020Article
- Differential patterns of definitive host use by two fish acanthocephalans occurring in sympatry:International journal for parasitology. Parasites and wildlife · 2019Article
- Winning the arms race: host-parasite shared evolutionary history reduces infection risks in fish final hosts.Biology letters · 2018Article
- Parasite infection and host personality:Behavioral ecology and sociobiology · 2018Article
- Anxiety-like behaviour increases safety from fish predation in an amphipod crustacea.Royal Society open science · 2017Article
- Host manipulation in the face of environmental changes: Ecological consequences.International journal for parasitology. Parasites and wildlife · 2015Article
- Influence of host nutritional condition on post-infection traits in the association between the manipulative acanthocephalan Pomphorhynchus laevis and the amphipod Gammarus pulex.Parasites & vectors · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Manipulative parasites often alter the phenotype of their hosts along multiple dimensions. 'Multidimensionality' in host manipulation could consist in the simultaneous alteration of several physiological pathways independently of one another, or proceed from the disruption of some key physiological parameter, followed by a cascade of effects. We compared multidimensionality in 'host manipulation' between two closely related amphipods, Gammarus fossarum and Gammarus pulex, naturally and experimentally infected with Pomphorhynchus laevis (Acanthocephala), respectively. To that end, we calculated in each host-parasite association the effect size of the difference between infected and uninfected individuals for six different traits (activity, phototaxis, geotaxis, attraction to conspecifics, refuge use and metabolic rate). The effects sizes were highly correlated between host-parasite associations, providing evidence for a relatively constant 'infection syndrome'. Using the same methodology, we compared the extent of phenotypic alterations induced by an experimental injection of serotonin (5-HT) in uninfected G. pulex to that induced by experimental or natural infection with P. laevis. We observed a significant correlation between effect sizes across the six traits, indicating that injection with 5-HT can faithfully mimic the 'infection syndrome'. This is, to our knowledge, the first experimental evidence that multidimensionality in host manipulation can proceed, at least partly, from the disruption of some major physiological mechanism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.