ReviewInternational journal of biometeorology2015
Spa therapy: can be a valid option for treating knee osteoarthritis?
Review in International journal of biometeorology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 10 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- Evidence-based balneotherapy in Hungary. Updated systematic review and meta-analysis of the Hungarian clinical trials.International journal of biometeorology · 2026Pooled it
- Clinical efficacy of medical hydrology: an umbrella review.International journal of biometeorology · 2021Pooled it
- Pooled it
- Efficacy of aquatic therapy for neck pain: a systematic review.International journal of biometeorology · 2020Pooled it
- Effects of balneotherapy and spa therapy on quality of life of patients with knee osteoarthritis: a systematic review and meta-analysis.Rheumatology international · 2018Pooled it
- Effects of balneotherapy and spa therapy on levels of cortisol as a stress biomarker: a systematic review.International journal of biometeorology · 2018Pooled it
- Efficacy of Spa Therapy, Mud-Pack Therapy, Balneotherapy, and Mud-Bath Therapy in the Management of Knee Osteoarthritis. A Systematic Review.BioMed research international · 2018Pooled it
- The role of mineral elements and other chemical compounds used in balneology: data from double-blind randomized clinical trials.International journal of biometeorology · 2017Pooled it
- Clinical Efficacy of Mudpack Therapy in Treating Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Studies.American journal of physical medicine & rehabilitation · 2016Pooled it
- Effectiveness of low-level laser therapy in patients with knee osteoarthritis: a systematic review and meta-analysis.Osteoarthritis and cartilage · 2015Pooled it
- 4-Week Comparative Outcomes of Standard Physiotherapy, Balneotherapy Plus Physiotherapy and Dextrose Prolotherapy in Patients with Low Back Pain: A Non-Randomized Study.Medicina (Kaunas, Lithuania) · 2026Trial
- Effects of serial thermal brine hand baths on hand osteoarthritis: a randomized, double-blind, sham-controlled trial.European journal of physical and rehabilitation medicine · 2026Trial
- Balneotherapy for knee osteoarthritis in S. Jorge: a randomized controlled trial.International journal of biometeorology · 2020Trial
- Balneotherapy for musculoskeletal pain: does the mineral content matter?International journal of biometeorology · 2020Trial
- Effect of balneotherapy on pain and fatigue in elderly with knee osteoarthritis receiving physical therapy: a randomized trial.International journal of biometeorology · 2019Trial
- Efficacy of self-management exercise program with spa therapy for behavioral management of knee osteoarthritis: research protocol for a quasi-randomized controlled trial (GEET one).BMC complementary and alternative medicine · 2018Trial
- Clinical improvement of patients with osteoarthritis using thermal mineral water at Szigetvár Spa-results of a randomised double-blind controlled study.International journal of biometeorology · 2018Trial
- Spa therapy adjunct to pharmacotherapy is beneficial in rheumatoid arthritis: a crossover randomized controlled trial.International journal of biometeorology · 2018Trial
- Spa therapy (balneotherapy) relieves mental stress, sleep disorder, and general health problems in sub-healthy people.International journal of biometeorology · 2018Trial
- The role of thermal balneotherapy in the treatment of obese patient with knee osteoarthritis.International journal of biometeorology · 2018Trial
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) continues to be one of the leading causes of 'years lived with disability' worldwide. Symptomatic knee OA is highly prevalent among people aged 50 years and over and is destined to become an ever more important healthcare problem. Current management of knee OA includes non-pharmacological and pharmacological treatments. Spa therapy is one of the most commonly used non-pharmacological approaches for OA in many European countries, as well as in Japan and Israel. Despite its long history and popularity, spa treatment is still the subject of debate and its role in modern medicine continues to be unclear. The objective of this review is to summarize the currently available information on clinical effects and mechanisms of action of spa therapy in knee OA. Various randomized controlled clinical trials (RCTs) were conducted to assess the efficacy and tolerability of balneotherapy and mud-pack therapy in patients with knee OA. Data from these clinical trials support a beneficial effect of spa therapy on pain, function and quality of life in knee OA that lasts over time, until 6-9 months after the treatment. The mechanisms by which immersion in mineral or thermal water or the application of mud alleviate suffering in OA are not fully understood. The net benefit is probably the result of a combination of factors, among which the mechanical, thermal and chemical effects are most prominent. In conclusion, spa therapy seems to have a role in the treatment of knee OA. Additional RCTs and further studies of mechanisms of action with high methodological quality are necessary to prove the effects of spa therapy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.