ArticleScientific reports2014
Identification of the role of a MAP kinase Tmk2 in Hypocrea jecorina (Trichoderma reesei).
Article in Scientific reports, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 60 citations in OpenAlex.
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- Mycoparasitism related targets of Tmk1 indicate stimulating regulatory functions of this MAP kinase in Trichoderma atroviride.Scientific reports · 2023Article
- Early cellular events and potential regulators of cellulase induction in Penicillium janthinellum NCIM 1366.Scientific reports · 2023Article
- Protein Kinase PoxMKK1 Regulates Plant-Polysaccharide-Degrading Enzyme Biosynthesis, Mycelial Growth and Conidiation inJournal of fungi (Basel, Switzerland) · 2023Article
- MAPkinases regulate secondary metabolism, sexual development and light dependent cellulase regulation in Trichoderma reesei.Scientific reports · 2023Article
- Serine-arginine protein kinase-like protein, SrpkF, stimulates both cellobiose-responsive and D-xylose-responsive signaling pathways in Aspergillus aculeatus.Current genetics · 2022Article
- From induction to secretion: a complicated route for cellulase production in Trichoderma reesei.Bioresources and bioprocessing · 2021Review
- Stress-Activated Protein Kinase Signalling Regulates Mycoparasitic Hyphal-Hyphal Interactions inJournal of fungi (Basel, Switzerland) · 2021Article
- The GPI-Anchored GH76 Protein Dfg5 Affects Hyphal Morphology and Osmoregulation in the MycoparasiteFrontiers in microbiology · 2021Article
- The High Osmolarity Glycerol Mitogen-Activated Protein Kinase regulates glucose catabolite repression in filamentous fungi.PLoS genetics · 2020Article
- Application of the human estrogen receptor within a synthetic transcription factor inFungal biology and biotechnology · 2020Article
- Transcriptome and proteome analyses reveal the regulatory networks and metabolite biosynthesis pathways during the development ofComputational and structural biotechnology journal · 2020Article
- STK-12 acts as a transcriptional brake to control the expression of cellulase-encoding genes in Neurospora crassa.PLoS genetics · 2019Article
- Developmental transcriptomics of Chinese cordyceps reveals gene regulatory network and expression profiles of sexual development-related genes.BMC genomics · 2019Article
- Fusion transcription factors for strong, constitutive expression of cellulases and xylanases inBiotechnology for biofuels · 2019Article
- The influence of feedstock characteristics on enzyme production inBiotechnology for biofuels · 2019Review
- The Duality of the MAPK Signaling Pathway in the Control of Metabolic Processes and Cellulase Production in Trichoderma reesei.Scientific reports · 2018Article
- Functional characterization of the upstream components of the Hog1-like kinase cascade in hyperosmotic and carbon sensing inBiotechnology for biofuels · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Despite the important role of MAPKs in signal transduction, their functions in the cellulase hyper-producing filamentous fungus Hypocrea jecorina haven't been studied except for the Hog1-like Tmk3. In this work, we constructed and explored the features of H. jecorina Δtmk2 to identify the role of this Slt2-homologous Tmk2. It is suggested from the results that Tmk2 is involved in cell wall integrity, sporulation and cellulase production. Although bearing similar roles in cell wall integrity maintenance, Tmk2 and Tmk3 appear to also have distinct functions: Tmk3 participates in high osmolarity resistance while Tmk2 does not; Tmk2 participates in sporulation but not Tmk3; Tmk3 is involved in promoting cellulase production while Tmk2 is involved in repressing cellulase formation. These studies provide the first insight into the function of Tmk2 in H. jecorina and contribute to understanding the signal transduction processes leading to the regulation of cellulase production in this important cellulase hyper-producer.
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