ArticleBMC infectious diseases2014
Tuberculosis recurrence in a high incidence setting for HIV and tuberculosis in Brazil.
Article in BMC infectious diseases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Time to reoccurrence of tuberculosis and its predictors among adult HIV/AIDS patients on ART at public hospitals in East and Horro Guduru Wollega zones, West Ethiopia: a retrospective cohort study.BMC public health · 2025Article
- Timing of recurrence after treatment of pulmonary TB.IJTLD open · 2024Article
- Decreased IL-1 β Secretion as a Potential Predictor of Tuberculosis Recurrence in Individuals Diagnosed with HIV.Biomedicines · 2024Article
- Clinical and laboratory risk factors for pulmonary tuberculosis recurrence in three pooled Indian cohorts.Frontiers in tuberculosis · 2024Article
- The impact of comorbidities on tuberculosis treatment outcomes in Poland: a national cohort study.Frontiers in public health · 2023Article
- Article
- Advancing our understanding of HIV co-infections and neurological disease using the humanized mouse.Retrovirology · 2021Review
- The Relevance of Genomic Epidemiology for Control of Tuberculosis in West Africa.Frontiers in public health · 2021Review
- The Effect of Long-Term HAART on the Incidence of Tuberculosis Among People Living with HIV in Addis Ababa, Ethiopia: A Matched Nested Case-Control Study.Infection and drug resistance · 2021Article
- Small Animal Model of Post-chemotherapy Tuberculosis Relapse in the Setting of HIV Co-infection.Frontiers in cellular and infection microbiology · 2020Article
- Decreased risk of HIV-associated TB during antiretroviral therapy expansion in rural Eswatini from 2009 to 2016: a cohort and population-based analysis.Tropical medicine & international health : TM & IH · 2019Article
- Recurrence Is a Noticeable Cause of Rifampicin-ResistantFrontiers in public health · 2019Article
- Classifying recurrent Mycobacterium tuberculosis cases in Georgia using MIRU-VNTR typing.PloS one · 2019Article
- Detection of tuberculosis drug resistance: a comparison by Mycobacterium tuberculosis MLPA assay versus Genotype®MTBDRplus.Memorias do Instituto Oswaldo Cruz · 2017Article
- FACTORS ASSOCIATED WITH TB/HIV CO-INFECTION AMONG DRUG SENSITIVE TUBERCULOSIS PATIENTS MANAGED IN A SECONDARY HEALTH FACILITY IN LAGOS, NIGERIA.African journal of infectious diseases · 2017Article
- Infection of multipleInternational journal of mycobacteriologyArticle
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Authors and funding
7 authors.
Funding
Abstract
backgroundTo compare epidemiological data between recurrent cases after cure (RC), distinguishing relapse from reinfection, after dropout (RD) and new cases (NC) in an ambulatory setting in a TB-endemic country.
methodsRecords of patients who started treatment for pulmonary TB between 2004 and 2010 in a TB clinic were reviewed. Epidemiological data were analyzed. Spoligotyping and MIRU patterns were used to determine relapse or reinfection in 13 RC available.
resultsOf the eligible group (1449), 1060 were NC (73.2%), among the recurrent cases, 203 (14%) were RC and 186 (12.8%) were RD. Of RC, 171 (84.2%) occurred later than 6 months after a previous episode, 13 had available DNA, in 4 (30.7%) the disease was attributed to reinfection and in 9 (69.3%), to relapse. Comparing RC to NC, HIV (p < 0.0001) was independent risk factor for RC. When RC and RD were compared, alcohol abuse (p = 0.001) and treatment noncompliance (p = 0.006) were more frequent in RD.
conclusionsHIV is the sole more important associated factor for RC. This finding points the need to improve the approach to manage TB in order to decrease the chance for exposure especially in vulnerable people with increased risk of developing disease and to improve DOTS strategy to deal with factors associated to treatment noncompliance.
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