Evidence map›Paper›PMID 25337971›Full record

ArticleJournal of assisted reproduction and genetics2015

Can we use incubators with atmospheric oxygen tension in the first phase of in vitro fertilization? A retrospective analysis.

Cristina Guarneri, Liliana Restelli, Alice Mangiarini, Stefania Ferrari, Edgardo Somigliana, Alessio Paffoni

Abstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Mechanisms of ovarian aging in women: a review.Journal of ovarian research · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cristina GuarneriInfertility Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via M. Fanti 6, 20122, Milan, Italy.
Liliana Restelli
Alice Mangiarini
Stefania Ferrari
Edgardo Somigliana
Alessio Paffoni

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAim of the present study was to compare two culture strategies used in our routine in vitro fertilization program.

methodsThis is a retrospective analysis. Two culture systems were used in parallel and analysed retrospectively: 1) Use of atmospheric oxygen tension (~20 %) until insemination followed by use of low (~5 %) oxygen concentration; 2) Exclusive use of low oxygen concentration. Main outcome was the utilization rate defined as the number of transferred + vitrified embryos per inseminated oocytes. Secondary outcomes were clinical pregnancy and live birth rates.

resultsA total of 402 in vitro fertilization cycles were analyzed. Demographic and clinical data of patients belonging to the two culture systems were not significantly different. Utilization rate, cumulative clinical pregnancy rate and cumulative live birth rate per cycle was similar using two different oxygen concentration compared to exclusive use of low oxygen tension (37 % versus 39 %; 30 % versus 30 %; 23 % versus 28 %, respectively).

conclusionsThe use of a culture system with atmospheric oxygen tension from recovery of oocytes until insemination followed by culture in low oxygen gives results similar to exclusive use of low oxygen concentration.

Indexed as

Fertilization in VitroBirth RateEmbryo Culture TechniquesFemaleHumansIncubatorsOocytesOxygenPregnancyPregnancy RateRetrospective StudiesVitrificationOxygen

Identifiers

PMID25337971
PMCPMC4294869

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.