Evidence map›Paper›PMID 25337948›Full record

Trial reportSleep2015

Internet treatment addressing either insomnia or depression, for patients with both diagnoses: a randomized trial.

Kerstin Blom, Susanna Jernelöv, Martin Kraepelien, Malin Olséni Bergdahl, Kristina Jungmarker, Linda Ankartjärn, Nils Lindefors, Viktor Kaldo

3 registry-linked trialsOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 73 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 5 pooled it
18.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01256099 nacompletednot on this map

Guided Internet-treatment for Insomnia. Treatment Effects, Health Economics and Interaction With Depression

TypeinterventionalSponsorKarolinska InstitutetRan2010 to 2015Enrolled191ConditionsInsomnia, DepressionArmsTherapist guided Internet-CBT for insomnia, Brief Internet-CBT for insomnia, without support, Therapist Guided Internet-CBT for depression
NCT04191811 recruitingnot on this mapstarted 2022, after this paper: background citation

Moment-to-moment Neural Variability as a Predictor of Treatment Outcome in Patients With Common Psychiatric Disorders: Major Depressive Disorder, Insomnia and Social Anxiety Disorder

TypeobservationalSponsorKarolinska InstitutetRan2022 to 2026Enrolled150ConditionsPsychiatric Disorder, Depression, Anxiety Disorders, InsomniaArmsInternet-delivered cognitive behavioral therapy for major depressive disorder, Internet-delivered cognitive behavioral therapy for insomnia, Internet-delivered cognitive behavioral therapy for social anxiety disorder
NCT05630261 naunknown statusnot on this mapstarted 2022, after this paper: background citation

Efficacy of Internet-based Transdiagnostic Cognitive Behavioural Therapy Insomnia (CBT-I) on Comorbid Depression and Insomnia: A Pilot Randomized Controlled Trial

TypeinterventionalSponsorChinese University of Hong KongRan2022 to 2023Enrolled100ConditionsInsomnia, DepressionArmsSelf-help CBT-I, Self-help CBT-D
3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 5 syntheses or guidelines pooled it, 193 citations in OpenAlex.

  1. Pooled it
  2. Cognitive and Behavioral Interventions to Improve Sleep in School-Age Children and Adolescents: A Systematic Review and Meta-Analysis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
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  15. A randomized controlled study of weighted chain blankets for insomnia in psychiatric disorders.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2020
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Kerstin BlomKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Susanna JernelövKarolinska Institutet, Department of Clinical Neuroscience, Section of Psychology, Stockholm, Sweden.
Martin KraepelienKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Malin Olséni BergdahlKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Kristina JungmarkerKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Linda AnkartjärnKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Nils LindeforsKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Viktor KaldoKarolinska Institutet, Department of Clinical Neuroscience, Division of Psychiatry, Stockholm, Sweden.
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesTo compare treatment effects when patients with insomnia and depression receive treatment for either insomnia or depression.

designA 9-w randomized controlled trial with 6- and 12-mo follow-up.

settingInternet Psychiatry Clinic, Stockholm, Sweden.

participantsForty-three adults in whom comorbid insomnia and depression were diagnosed, recruited via media and assessed by psychiatrists.

interventionsGuided Internet-delivered cognitive behavior therapy (ICBT) for either insomnia or depression. MEASUREMENTS AND

resultsPrimary outcome measures were symptom self-rating scales (Insomnia Severity Index [ISI] and the Montgomery Åsberg Depression Rating Scale [MADRS-S]), assessed before and after treatment with follow-up after 6 and 12 mo. The participants' use of sleep medication and need for further treatment after completion of ICBT was also investigated. The insomnia treatment was more effective than the depression treatment in reducing insomnia severity during treatment (P = 0.05), and equally effective in reducing depression severity. Group differences in insomnia severity were maintained during the 12-mo follow-up period. Post treatment, participants receiving treatment for insomnia had significantly less self-rated need for further insomnia treatment (P < 0.001) and used less sleep medication (P < 0.05) than participants receiving treatment for depression. The need for depression treatment was similar in both groups.

conclusionsIn this study, Internet-delivered treatment with cognitive behavior therapy (ICBT) for insomnia was more effective than ICBT for depression for patients with both diagnoses. This indicates, in line with previous research, that insomnia when comorbid with depression is not merely a symptom of depression, but needs specific treatment.

trial registrationThe trial was registered at Clinicaltrials.gov, registration ID: NCT01256099.

Indexed as

Cognitive Behavioral TherapyInternetDepressionDepressive DisorderFemaleFollow-Up StudiesHumansMaleMiddle AgedSleep Initiation and Maintenance DisordersSwedenTreatment OutcomeCBTcomorbiditydepressioninsomniaInternetpsychological treatmentpsychotherapy

Identifiers

PMID25337948
PMCPMC4288608
OpenAlexW2081302185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.