Evidence map›Paper›PMID 25337849›Full record

ArticleAsian journal of andrology

To screen or nor to screen: the prostate cancer dilemma.

Nelson N Stone, E David Crawford

Abstract readComment
In one paragraph

Article in Asian journal of andrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cancer prevention: state of the art and future prospects.Journal of preventive medicine and hygiene · 2015
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nelson N StoneDepartment of Urology and Radiation Oncology, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.
E David Crawford

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The European Randomized Study of Screening for Prostate (ERSPC) has updated their previous seminal report on prostate cancer mortality comparing screened men to controls. Now with 13 years follow-up, the rate ratio of prostate cancer mortality was 0.79 favoring the screened population. The authors concluded that there was a "substantial reduction in prostate cancer mortality attributable to testing with prostate-specific antigen (PSA)" but they also stated that a "quantification of harms" needed to be addressed. The issue of harms was not addressed by the ERSPC (at least not in this report) and hence this additional statement most likely reflects the controversy currently surrounding the risks associated with over-diagnosis and treatment of indolent diseases inadvertently detected by a screening protocol. [1] In addition, the positive results from this trial conflict with those of the prostate, lung, colorectal and ovarian (PLCO) [2] study and require further elaboration.

Indexed as

Early Detection of CancerQuality-Adjusted Life YearsQuality of LifeHumansMaleProstate-Specific AntigenProstatic NeoplasmsProstate-Specific Antigen

Identifiers

PMID25337849
PMCPMC4291875

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.