Evidence map›Paper›PMID 25337773›Full record

ArticleKidney international2015

Racial and ethnic disparities in pediatric renal allograft survival in the United States.

Rachel E Patzer, Sumit Mohan, Nancy Kutner, William M McClellan, Sandra Amaral

Open access · bronzeAbstract read
In one paragraph

Article in Kidney international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

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  18. Relationship between antithymocyte globulin, T cell phenotypes, and clinical outcomes in pediatric kidney transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2021
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rachel E Patzer1] Department of Surgery, Division of Transplantation, Emory University School of Medicine, Emory University, Atlanta, Georgia, USA [2] Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York, USA.
Nancy KutnerDepartment of Rehabilitation Medicine, Emory University, Atlanta, Georgia, USA.
William M McClellan1] Department of Surgery, Division of Transplantation, Emory University School of Medicine, Emory University, Atlanta, Georgia, USA [2] Division of Nephrology, Emory University, Atlanta, Georgia, USA.
Sandra Amaral1] Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, Philadelphia, USA [2] Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Philadelphia, USA.
Emory University · USChildren's Hospital of Philadelphia · USColumbia University Irving Medical Center · US

Funding

Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalKL2TR000455 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$2.9M
A regionally coordinated intervention to reduce racial disparities in access to kR24MD008077 · NIMHD · EMORY UNIVERSITY · PI PATZER, RACHEL E · 2013 to 2015
$916k
Assessing an adherence intervention for adolescents with kidney transplantsK23DK083529 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI AMARAL, SANDRA · 2011 to 2015
$861k
NCATS NIH HHS KL2 TR000455NCATS NIH HHS KL2TR000455NCATS NIH HHS UL1 TR000454NCATS NIH HHS ULL TR000454NIDDK NIH HHS K23 DK083529NIDDK NIH HHS K23-DK083529NIMHD NIH HHS L60 MD007236NIMHD NIH HHS R24 MD008077NIMHD NIH HHS R24MD008077
6 · The paper itself

Abstract

This study was undertaken to describe the association of patient race/ethnicity and renal allograft survival among the national cohort of pediatric renal allograft recipients. Additionally, we determined whether racial and ethnic differences in graft survival exist among individuals living in low- or high-poverty neighborhoods and those with private or public insurance. Among 6216 incident, pediatric end-stage renal disease patients in the United States Renal Data System (kidney transplant from 2000 through September, 2011), 14.4% experienced graft failure, with a median follow-up time of 4.5 years. After controlling for multiple covariates, black race, but not Hispanic ethnicity, was significantly associated with a higher rate of graft failure for both deceased and living donor transplant recipients. Disparities were particularly stark by 5 years post transplant, when black living donor transplant recipients experienced only 63.0% graft survival compared with 82.8 and 80.8% for Hispanics and whites, respectively. These disparities persisted among high- and low-poverty neighborhoods and among both privately and publicly insured patients. Notably profound declines in both deceased and living donor graft survival rates for black, compared with white and Hispanic, children preceded the 3-year mark when transplant Medicare eligibility ends. Further research is needed to identify the unique barriers to long-term graft success among black pediatric transplant recipients.

Indexed as

Graft SurvivalHealth Status DisparitiesAdolescentAllograftsBlack or African AmericanChildChild, PreschoolFemaleGraft RejectionHispanic or LatinoHumansInfantInfant, NewbornKidney Failure, ChronicKidney TransplantationLiving Donors

Identifiers

PMID25337773
PMCPMC4344895
OpenAlexW2048425111

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.