ArticleBasic and clinical neuroscience2014
Effect of Extremely Low Frequency Electromagnetic Field and/or GABAB Receptors on Foot Shock-induced Aggression in Rats.
Article in Basic and clinical neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
- Pulsed electromagnetic field attenuated PTSD-induced failure of conditioned fear extinction.Iranian journal of basic medical sciences · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe present study investigated the interactive effect of GABAB receptors and extremely low frequency electromagnetic field (ELF-EMF) on foot shock-induced aggression in rats.
methodsFifty adult male rats were randomly assigned into 10 groups. Groups 2, 4, 6, 8 and 10 were exposed to 50 Hz, 500 µT ELF-EMF for 30 days 8h per day while the remaining groups (1, 3, 5, 7 and 9) were sham-exposed. At the end of this period, the animals in groups 1 and 2 received normal saline while groups 3 and 4 treated with 100 mg/kg (low dose) of CGP35348 and groups 5 and 6 injected with 200 mg/kg (high dose) of CGP35348. Groups 7 and 8 treated with 1.7 mg/kg (low dose) of Baclofen and groups 9 and 10 received 3 mg/kg (high dose) Baclofen by IP injections. Twenty min after the injection, the aggressive behavior was recorded in foot shock-induced aggression model. The number of lateral threat, lifted up threat, biting, attacking, chasing and approaching were considered as paradigms of aggressive behavior.
resultsELF-EMF, Baclofen or CGP35348 alone had no significant effect on aggressive behavior. Except that rats exposed and treated with low dose of CGP35348 demonstrated significantly higher numbers of only one of the paradigms of aggressive behavior (lifted up threats), CGP35348 and Baclofen in both doses in combination with ELF-EMF exposure had no significant effect on aggression. DISCUSSION: GABAB receptors and ELF-EMFs had no effect (both enhancement and suppression) on aggressive behavior of rats in foot shock-induced model of aggression.
Indexed as
Identifiers
25337376PMC4202593W341018217What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.