ArticleBasic and clinical neuroscience2013
2D Computational Fluid Dynamic Modeling of Human Ventricle System Based on Fluid-Solid Interaction and Pulsatile Flow.
Article in Basic and clinical neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Fluid dynamics model of the cerebral ventricular system.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Neuroendoscopic cyst fenestration for delayed enlargement of perianeurysmal cyst formation through long-term follow-up after endovascular treatment: A case report and review of literature.Surgical neurology international · 2024Article
- Primary central nervous system lymphoma of the third ventricle with intra-tumoral hemorrhage: A case report and literature review.Oncology letters · 2023Article
- Influence of interaction of cerebral fluids on ventricular deformation: A mathematical approach.PloS one · 2022Article
- Changes in Tongue Area, Pharyngeal Area, and Pharyngeal Airway Velocity after Correction of Mandibular Prognathism.Journal of clinical medicine · 2021Article
- How growing tumour impacts intracranial pressure and deformation mechanics of brain.Royal Society open science · 2021Article
- Brain ventricular volume changes induced by long-duration spaceflight.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Finite Element Framework for Computational Fluid Dynamics in FEBio.Journal of biomechanical engineering · 2018Article
- Nasoethmoid-nasoorbital encephalocele presenting with orbital pulsation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many diseases are related to cerebrospinal fluid (CSF) hydrodynamics. Therefore, understanding the hydrodynamics of CSF flow and intracranial pressure is helpful for obtaining deeper knowledge of pathological processes and providing better treatments. Furthermore, engineering a reliable computational method is promising approach for fabricating in vitro models which is essential for inventing generic medicines. A Fluid-Solid Interaction (FSI)model was constructed to simulate CSF flow. An important problem in modeling the CSF flow is the diastolic back flow. In this article, using both rigid and flexible conditions for ventricular system allowed us to evaluate the effect of surrounding brain tissue. Our model assumed an elastic wall for the ventricles and a pulsatile CSF input as its boundary conditions. A comparison of the results and the experimental data was done. The flexible model gave better results because it could reproduce the diastolic back flow mentioned in clinical research studies. The previous rigid models have ignored the brain parenchyma interaction with CSF and so had not reported the back flow during the diastolic time. In this computational fluid dynamic (CFD) analysis, the CSF pressure and flow velocity in different areas were concordant with the experimental data.
Indexed as
Identifiers
25337330PMC4202551What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.