Evidence map›Paper›PMID 25337280›Full record

ArticleInternational journal of clinical and experimental pathology2014

Liofilchem(®) Chromatic VRE and vancomycin MIC Test Strip detected glycopeptide resistance in a vanB neonatal Enterococcus faecium isolate showing alternate vancomycin susceptibility and resistance with bioMérieux Vitek2.

Vincenzo Savini, Roberta Marrollo, Eleonora Coclite, Paola Fusilli, Carmine D'Incecco, Paolo Fazii, Giovanni Gherardi

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Vincenzo SaviniClinical Microbiology and Virology, Spirito Santo Hospital Pescara (Pe), Italy.
Roberta MarrolloClinical Microbiology and Virology, Spirito Santo Hospital Pescara (Pe), Italy.
Eleonora CocliteNeonatal Intensive Care Unit and Neonatal Pathology, Spirito Santo Hospital Pescara (PE), Italy.
Paola FusilliNeonatal Intensive Care Unit and Neonatal Pathology, Spirito Santo Hospital Pescara (PE), Italy.
Carmine D'InceccoNeonatal Intensive Care Unit and Neonatal Pathology, Spirito Santo Hospital Pescara (PE), Italy.
Paolo FaziiClinical Microbiology and Virology, Spirito Santo Hospital Pescara (Pe), Italy.
Giovanni GherardiIntegrated Research Centre, University Campus Biomedico Rome (RM), Italy.
Ospedale di Santo Spirito · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 1-month old neonate urine sample yielded vanB Enterococcus faecium; nevertheless, the isolate alternatively showed susceptibility and resistance to vancomycin with bioMérieux Vitek2 (cards AST592, AST632, AST586), while glycopeptide resistance was detected by Liofilchem(®) vancomycin MIC Test Strip and disc along with the Chromatic VRE chromogenic medium. This communication emphasizes that, as vanB gene may be heterogeneously expressed within a given Enterococcus population, glycopeptide resistance may be missed when using automated systems for antibiotic susceptibility testing. We suggest therefore that vancomycin in vitro activity be studied on all clinical isolates through agar methods, including use of chromogenic media.

Indexed as

Reagent StripsAutomation, LaboratoryBacterial ProteinsDisk Diffusion Antimicrobial TestsDrug Resistance, Multiple, BacterialEnterococcus faeciumGenotypeGram-Positive Bacterial InfectionsHumansInfant, NewbornMaleMicrobial Sensitivity TestsPredictive Value of TestsReproducibility of ResultsUrinary Tract InfectionsUrineBacterial ProteinsReagent StripsVanB protein, EnterococcusEnterococcus faeciumglycopeptideneonatenewbornvanBvancomycin

Identifiers

PMID25337280
PMCPMC4203251
OpenAlexW2290337097

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.