Evidence map›Paper›PMID 25337279›Full record

SynthesisInternational journal of clinical and experimental pathology2014

Thyroid cancer in systemic lupus erythematosus: a meta analysis.

Min Zhang, Xiao-Mei Li, Guo-Sheng Wang, Long Qian, Jin-Hui Tao, Yan Ma, Xiang-Pei Li

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. A review on SLE and malignancy.Best practice & research. Clinical rheumatology · 2017
    Review
  10. Review
  11. Article
  12. Risk Factors ofThe Journal of clinical endocrinology and metabolism · 2016
    Article
  13. Review
  14. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Min ZhangDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Xiao-Mei LiDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Guo-Sheng WangDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Long QianDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Jin-Hui TaoDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Yan MaDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Xiang-Pei LiDepartment of Rheumatology and Immunology, Anhui Provincial Hospital, Anhui Medical University Hefei 230001, P. R. China.
Anhui Provincial Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveConsidering inconclusive and heterogenous results, the aim of this study was to investigate the risk of thyroid cancer in systemic lupus erythematosus (SLE) by a quantitatively systematic review with meta-analysis.

methodsElectronic database of PubMed was searched for studies characterizing the associated risk of thyroid cancer in patients with SLE. The meta-analysis procedure was used to combine standardized incidence rates (SIRs) with 95% confidence intervals (CIs) to evaluate the association.

resultsSeven cohort studies fulfilled the inclusion criteria and were subjected to the final analysis in the meta-analysis. Homogeneity was confirmed across the included studies. The pooled SIR based on a fixed-effect model was 2.22, with a 95% CI of 2.11-2.34. Sensitivity analyses suggested that the summary statistics obtained should approximate the actual average.

conclusionFindings from this meta-analysis revealed the positive association between thyroid cancer and SLE risk. Individuals with SLE have a heightened risk of developing thyroid cancer.

Indexed as

Chi-Square DistributionHumansIncidenceLupus Erythematosus, SystemicRisk AssessmentRisk FactorsThyroid NeoplasmsMeta-analysisstandardized incidence ratiosystemic lupus erythematosusthyroid cancer

Identifiers

PMID25337279
PMCPMC4203250
OpenAlexW2369298523

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.