Evidence map›Paper›PMID 25337182›Full record

SynthesisInternational journal of clinical and experimental pathology2014

Risk factors influencing the recurrence of papillary thyroid carcinoma: a systematic review and meta-analysis.

Kai Guo, Zhuoying Wang

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC
In one paragraph

Synthesis in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kai GuoDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center Shanghai 200032, China ; Department of Oncology, Fudan University Shanghai Medical College Shanghai 200032, China.
Zhuoying WangDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center Shanghai 200032, China ; Department of Oncology, Fudan University Shanghai Medical College Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the risk factors influencing the recurrence of papillary thyroid carcinoma.

methodsThis meta-analysis used MEDLINE (PubMed), EMBASE and CNKI including all cohort studies reporting the risk factors influencing the recurrence after the initial operation on PTC up to February 23, 2014. Software RevMan 5.2 was used for meta-analysis.

resultsThirteen studies with a total of 7048 patients were included in our meta-analysis. Of all variables, gender, extrathyroid extension, LNM, tumor size, distance metastasis, thyroid surgery types and 131-I given or not were significantly correlated with recurrence, While overall recurrence was similar between the group of ≤ 45 years and > 45 years, multifolicality and solitary. However, when stratified the participants by study location (ie, Asian including China, Korea, Japan, Western country including America, France, Italy, Australia), a statistically significant summary odds ratio for age were found in Western country but none in Asian.

conclusionThe risk factors influencing recurrence includes male, extrathyroid extension, LNM, tumor size more than 2 cm, distance metastasis and subtotal thyroidectomy. However, selection of operation mode should be based on not only the recurrence but the comprehensive consideration of the clinical features.

Indexed as

Neoplasm Recurrence, LocalThyroidectomyAdultAge FactorsCarcinomaCarcinoma, PapillaryChi-Square DistributionFemaleHumansLymphatic MetastasisMaleMiddle AgedNeoplasm StagingOdds RatioRisk FactorsSex FactorsPapillary thyroid carcinomarecurrencerisk factors

Identifiers

PMID25337182
PMCPMC4203153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.