Evidence map›Paper›PMID 25337141›Full record

ArticleHepatitis monthly2014

Occult hepatitis C virus infection in patients with autoimmune hepatitis.

Mohammad Saeid Rezaee Zavareh, Seyed Moayed Alavian, Hamidreza Karimisari, Mostafa Shafiei, Seyed Yasser Saiedi Hosseini

Open access · hybridAbstract read
In one paragraph

Article in Hepatitis monthly, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. [Histological evaluation of liver in chronic hepatitis C after direct-acting antiviral agents treatment].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2018
    Article
  3. Article
  4. Review
  5. Article
  6. Occult HCV Infection: The Current State of Knowledge.Iranian Red Crescent medical journal · 2015
    Review
  7. Epidemiology of hepatitis C virus in Iran.World journal of gastroenterology · 2015
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mohammad Saeid Rezaee ZavarehStudents' Research Committee, Baqiyatallah University of Medical Sciences, Tehran, IR Iran ; Middle East Liver Diseases Center (MELD), Tehran, IR Iran.
Seyed Moayed AlavianMiddle East Liver Diseases Center (MELD), Tehran, IR Iran.
Hamidreza KarimisariStudents' Research Committee, Baqiyatallah University of Medical Sciences, Tehran, IR Iran.
Mostafa ShafieiMiddle East Liver Diseases Center (MELD), Tehran, IR Iran.
Seyed Yasser Saiedi HosseiniMiddle East Liver Diseases Center (MELD), Tehran, IR Iran.
Middle East Liver Disease Center · IRBaqiyatallah University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOccult hepatitis C virus infection (OCI) is recognized by finding hepatitis C virus (HCV) RNA in hepatocytes without detectable anti-HCV antibodies and viral RNA in plasma. Autoimmune hepatitis (AIH) is a chronic and generally progressive disease without exactly-identified etiology.

objectivesThis study aimed to determine the prevalence of OCI among patients with AIH and to evaluate the tests used to rule out HCV infection in diagnosing AIH. PATIENTS AND

methodsBetween July 2012 to February 2013, 35 Iranian patients with AIH who attended Tehran Hepatitis Center were investigated. For identifying OCI, detection of HCV RNA in both ultracentrifuged serum samples and peripheral blood mononuclear cells (PBMCs) was used. Data analysis was performed using SPSS.

resultsSix males and 29 females with mean disease duration of 77.1 ± 39.5 month and mean age of 43.62 ± 12.67 years were investigated. All cases were negative for anti-HCV antibody and we could not find any HCV RNA in ultracentrifuged serum samples and PBMCs.

conclusionsWith our laboratory diagnostic method, it seems that there are no cases of OCI in patients with AIH. However, we recommend further studies with more samples and more precise laboratory method.

Indexed as

Autoimmune HepatitisClinical Laboratory TechniqueDiagnosisHepatitis C virusInfectionPrevalence

Identifiers

PMID25337141
PMCPMC4199148
OpenAlexW2166597346

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.