Evidence map›Paper›PMID 25336881›Full record

ArticleHippokratia2014

Patient-specific arterial system flow oscillation.

Dk Fytanidis, Jv Soulis, Gd Giannoglou

Abstract read
In one paragraph

Article in Hippokratia, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dk FytanidisFluid Mechanics Division, School of Engineering, Democrition University of Thrace, Xanthi, Greece.
Jv SoulisFluid Mechanics Division, School of Engineering, Democrition University of Thrace, Xanthi, Greece.
Gd GiannoglouCardiovascular Engineering and Atherosclerosis Laboratory, 1 Cardiology Department, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtherosclerosis formation depends on the biomechanical blood flow properties. The temporal variation during the cardiac cycle has been proposed as a decisive atherogenic factor. Patient-specific (complex configuration) of the vessel promotes flow disturbances. The present study analyses the factors simulating pulsatile blood flow in the human arterial system using patient-specific geometry.

methodsWith the aid of numerical techniques, we examine the relation between time-Averaged Wall Shear Stress (AWSS), time-Averaged Wall Shear Stress Vector (AWSSV), Oscillatory Shear Index (OSI) and Relative Residence Time (RRT).

resultsThe velocity vector oscillates and at the same time alters its direction in places with low AWSS values. Low AWSS and high OSI values do not always collocate. AWSSV tends to alter its values, compared to AWSS, in regions where AWSS is low. RRT present high values in areas with low AWSS. The inverse proportionality relation between RRT and AWSSV is established.

conclusionsRegional differences between AWSS magnitude, OSI and RRT, may answer the question as to where atherosclerotic lesions predominately develop and progress at specific aortic regions. This analysis gives information for deeper understanding of the atherosclerosis mechanisms.

Identifiers

PMID25336881
PMCPMC4201404

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.