ArticleAdvanced healthcare materials2015
Plasmonic nanodiamonds: targeted core-shell type nanoparticles for cancer cell thermoablation.
Article in Advanced healthcare materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 49 citations in OpenAlex.
- Hybrid plasmonic nanodiamonds for thermometry and local photothermal therapy of melanoma: a comparative study.Nanophotonics (Berlin, Germany) · 2024Article
- Widefield Diamond Quantum Sensing with Neuromorphic Vision Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Multimodal bioimaging using nanodiamond and gold hybrid nanoparticles.Scientific reports · 2022Article
- Metastable Brominated Nanodiamond Surface Enables Room Temperature and Catalysis-Free Amine Chemistry.The journal of physical chemistry letters · 2022Article
- Extremely rapid isotropic irradiation of nanoparticles with ions generated in situ by a nuclear reaction.Nature communications · 2018Article
- Improved emission of SiV diamond color centers embedded into concave plasmonic core-shell nanoresonators.Scientific reports · 2017Article
- Nanodiamonds: The intersection of nanotechnology, drug development, and personalized medicine.Science advances · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
Abstract
Targeted biocompatible nanostructures with controlled plasmonic and morphological parameters are promising materials for cancer treatment based on selective thermal ablation of cells. Here, core-shell plasmonic nanodiamonds consisting of a silica-encapsulated diamond nanocrystal coated in a gold shell are designed and synthesized. The architecture of particles is analyzed and confirmed in detail using electron tomography. The particles are biocompatibilized using a PEG polymer terminated with bioorthogonally reactive alkyne groups. Azide-modified transferrin is attached to these particles, and their high colloidal stability and successful targeting to cancer cells overexpressing the transferrin receptor are demonstrated. The particles are nontoxic to the cells and they are readily internalized upon binding to the transferrin receptor. The high plasmonic cross section of the particles in the near-infrared region is utilized to quantitatively ablate the cancer cells with a short, one-minute irradiation by a pulse 750-nm laser.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.