SynthesisClinical research in cardiology : official journal of the German Cardiac Society2015
Impact of sleep-disordered breathing and efficacy of positive airway pressure on mortality in patients with chronic heart failure and sleep-disordered breathing: a meta-analysis.
Synthesis in Clinical research in cardiology : official journal of the German Cardiac Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Non-invasive positive pressure ventilation for central sleep apnoea in adults.The Cochrane database of systematic reviews · 2022Pooled it
- Positive airway pressure therapy for the treatment of central sleep apnoea associated with heart failure.The Cochrane database of systematic reviews · 2019Pooled it
- Adaptive Servo-Ventilation for Central Sleep Apnea in Systolic Heart Failure.The New England journal of medicine · 2015Trial
- Adaptive servo ventilation for sleep apnoea in heart failure: the FACE study 3-month data.Thorax · 2022Observational
- Adaptive support ventilation as an effective treatment option for central sleep apnea in an older adult with heart failure with preserved ejection fraction: a case report.BMC geriatrics · 2022Article
- Obstructive sleep apnea versus central sleep apnea: prognosis in systolic heart failure.Cardiovascular diagnosis and therapy · 2020Article
- Epicardial fat accumulation is an independent marker of impaired heart rate recovery in obese patients with obstructive sleep apnea.Clinical research in cardiology : official journal of the German Cardiac Society · 2019Article
- Increased mortality and ICD therapies in ischemic versus non-ischemic dilated cardiomyopathy patients with cardiac resynchronization having survived until first device replacement.Archives of medical science : AMS · 2019Article
- Epidemiology of Sleep-Disordered Breathing and Heart Failure: What Drives What.Current heart failure reports · 2017Review
- Whom are we treating with adaptive servo-ventilation? A clinical post hoc analysis.Clinical research in cardiology : official journal of the German Cardiac Society · 2017Article
- Association between central sleep apnea and left ventricular structure: the Multi-Ethnic Study of Atherosclerosis.Journal of sleep research · 2017Article
- Cardioversion of atrial fibrillation or atrial flutter into sinus rhythm reduces nocturnal central respiratory events and unmasks obstructive sleep apnoea.Clinical research in cardiology : official journal of the German Cardiac Society · 2016Observational
- The Link Between Obstructive Sleep Apnea and Cardiovascular Disease.Current atherosclerosis reports · 2016Review
- High prevalence of peripheral arterial disease in patients with obstructive sleep apnoea.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
- Should All Congestive Heart Failure Patients Have a Routine Sleep Apnea Screening? Con.The Canadian journal of cardiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundsTo conduct a meta-analysis to investigate whether sleep-disordered breathing (SDB) is an independent risk factor for mortality and whether positive airway pressure (PAP) decreases mortality in patients with chronic heart failure (HF). The impact of SDB and the effects of PAP on mortality in patients with chronic HF remain unclear.
methodsWe searched the MEDLINE, EMBASE, and Cochrane databases. Clinical trials that addressed mortality and the effect of PAP on mortality in chronic HF patients with SDB were included in this meta-analysis.
resultsEleven studies (1,944 participants in total) that addressed mortality in chronic HF patients with SDB were included in this study. Patients with SDB showed a significantly increased mortality risk compared to those without SDB [risk ratio (RR) 1.66 (1.19-2.31)]. In sub-analyses, a significant increase in risk of mortality was observed for central sleep apnea versus no-SDB [RR 1.48 (1.15-1.91)], whereas no significant increase in risk was observed for obstructive sleep apnea versus no-SDB. Five randomized controlled studies (395 participants) that assessed the effect of PAP in chronic HF patients with SDB were analyzed. Adaptive servo-ventilation (ASV) significantly reduced all-cause mortality in chronic HF patients with SDB [RR 0.13 (0.02-0.95)], whereas continuous PAP did not significantly reduce all-cause mortality [RR 0.71 (0.32-1.57)].
conclusionsThe prevalence of SDB in patients with chronic HF is associated with worse survival, and ASV reduces all-cause mortality in patients with chronic HF concomitant with SDB.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.