Evidence map›Paper›PMID 25335783›Full record

Trial reportBMC research notes2014

The prevention of mother-to-child transmission of HIV cascade analysis tool: supporting health managers to improve facility-level service delivery.

Sarah Gimbel, Joachim Voss, Mary Anne Mercer, Brenda Zierler, Stephen Gloyd, Maria de Joana Coutinho, Florencia Floriano, Maria de Fatima Cuembelo, Jennifer Einberg, Kenneth Sherr

2 registry-linked trialsAbstract readClinical Trial
In one paragraph

Trial report in BMC research notes, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02023658 nacompletednot on this map

Systems Analysis and Improvement to Optimize pMTCT: A Cluster Randomized Trial

TypeinterventionalSponsorUniversity of WashingtonRan2014 to 2015Enrolled36ConditionsHIVArmspMTCT systems analysis and improvement
NCT03425136 nacompletednot on this mapstarted 2018, after this paper: background citation

Scaling up the Systems Analysis and Improvement Approach for Prevention of Mother-to-Child HIV Transmission in Mozambique

TypeinterventionalSponsorUniversity of WashingtonRan2018 to 2022Enrolled36ConditionsHIVArmsSystems Analysis and Improvement Approach (SAIA)
3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  11. Evaluating elimination of mother-to-child transmission of HIV in Suriname: a mixed method study.Revista panamericana de salud publica = Pan American journal of public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sarah GimbelDepartment of Family Child Nursing, University of Washington, Box 357262, Seattle, USA. sgimbel@uw.edu.
Joachim Voss
Mary Anne Mercer
Brenda Zierler
Stephen Gloyd
Maria de Joana Coutinho
Florencia Floriano
Maria de Fatima Cuembelo
Jennifer Einberg
Kenneth Sherr

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
Systems Analysis and Improvement to Optimize pMTCT: A Cluster Randomized TrialR01HD075057 · NICHD · UNIVERSITY OF WASHINGTON · PI SHERR, KENNETH · 2012 to 2014
$1.4M
HEALTH SYSTEMS STRENGTHENING TO IMPROVE HEALTH OUTCOMES: APPLYING IMPLEMENTATIONK02TW009207 · FIC · UNIVERSITY OF WASHINGTON · PI SHERR, KENNETH · 2011 to 2015
$403k
FIC NIH HHS K02 TW009207NIAID NIH HHS P30 AI027757NIAID NIH HHS P30AI027757NICHD NIH HHS R01 HD075057NICHD NIH HHS R01HD075057
6 · The paper itself

Abstract

backgroundThe objective of the prevention of Mother-to-Child Transmission (pMTCT) cascade analysis tool is to provide frontline health managers at the facility level with the means to rapidly, independently and quantitatively track patient flows through the pMTCT cascade, and readily identify priority areas for clinic-level improvement interventions. Over a period of six months, five experienced maternal-child health managers and researchers iteratively adapted and tested this systems analysis tool for pMTCT services. They prioritized components of the pMTCT cascade for inclusion, disseminated multiple versions to 27 health managers and piloted it in five facilities. Process mapping techniques were used to chart PMTCT cascade steps in these five facilities, to document antenatal care attendance, HIV testing and counseling, provision of prophylactic anti-retrovirals, safe delivery, safe infant feeding, infant follow-up including HIV testing, and family planning, in order to obtain site-specific knowledge of service delivery.

resultsSeven pMTCT cascade steps were included in the Excel-based final tool. Prevalence calculations were incorporated as sub-headings under relevant steps. Cells not requiring data inputs were locked, wording was simplified and stepwise drop-offs and maximization functions were included at key steps along the cascade. While the drop off function allows health workers to rapidly assess how many patients were lost at each step, the maximization function details the additional people served if only one step improves to 100% capacity while others stay constant.

conclusionsOur experience suggests that adaptation of a cascade analysis tool for facility-level pMTCT services is feasible and appropriate as a starting point for discussions of where to implement improvement strategies. The resulting tool facilitates the engagement of frontline health workers and managers who fill out, interpret, apply the tool, and then follow up with quality improvement activities. Research on adoption, interpretation, and sustainability of this pMTCT cascade analysis tool by frontline health managers is needed.

trial registrationClinicalTrials.gov NCT02023658, December 9, 2013.

Indexed as

Health PersonnelMothersChildDelivery of Health CareFemaleGeographyHealth FacilitiesHIV InfectionsHumansInfectious Disease Transmission, VerticalMozambiquePostnatal CarePregnancyPregnancy Complications, Infectious

Identifiers

PMID25335783
PMCPMC4216351

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.