Evidence map›Paper›PMID 25335773›Full record

ArticlePharmacoepidemiology and drug safety2015

Coding algorithms for identifying patients with cirrhosis and hepatitis B or C virus using administrative data.

Bolin Niu, Kimberly A Forde, David S Goldberg

Abstract read
In one paragraph

Article in Pharmacoepidemiology and drug safety, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
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  3. Drive time to care and retention in HIV care: Rural-urban differences among Medicaid enrollees in the United States South.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  4. Article
  5. Hepatocellular Carcinoma Surveillance among Individuals with Cirrhosis: Trends by Payer, Etiology, and Calendar Year, from a Statewide, Multi-Payer Dataset, 2010-2018.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Bolin NiuDepartment of Medicine, University of Pennsylvania, Philadelphia, PA, United States.
Kimberly A Forde
David S Goldberg

Funding

Gender and hormonal influences on liver fibrosis after transplant for hepatitis CK23DK090209 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FORDE, KIMBERLY AUTUMN · 2012 to 2016
$911k
A population-based cohort to study outcomes in end-stage liver disease patientsK08DK098272 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GOLDBERG, DAVID SETH · 2013 to 2017
$786k
NIDDK NIH HHS 1K08DK098272-01A1NIDDK NIH HHS K08 DK098272NIDDK NIH HHS K23 DK090209NIDDK NIH HHS K23DK090209
6 · The paper itself

Abstract

BACKGROUND AND

aimsDespite the use of administrative data to perform epidemiological and cost-effectiveness research on patients with hepatitis B or C virus (HBV, HCV), there are no data outside of the Veterans Health Administration validating whether International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) codes can accurately identify cirrhotic patients with HBV or HCV. The validation of such algorithms is necessary for future epidemiological studies.

methodsWe evaluated the positive predictive value (PPV) of ICD-9-CM codes for identifying chronic HBV or HCV among cirrhotic patients within the University of Pennsylvania Health System, a large network that includes a tertiary care referral center, a community-based hospital, and multiple outpatient practices across southeastern Pennsylvania and southern New Jersey. We reviewed a random sample of 200 cirrhotic patients with ICD-9-CM codes for HCV and 150 cirrhotic patients with ICD-9-CM codes for HBV.

resultsThe PPV of 1 inpatient or 2 outpatient HCV codes was 88.0% (168/191, 95% CI: 82.5-92.2%), while the PPV of 1 inpatient or 2 outpatient HBV codes was 81.3% (113/139, 95% CI: 73.8-87.4%). Several variations of the primary coding algorithm were evaluated to determine if different combinations of inpatient and/or outpatient ICD-9-CM codes could increase the PPV of the coding algorithm.

conclusionsICD-9-CM codes can identify chronic HBV or HCV in cirrhotic patients with a high PPV and can be used in future epidemiologic studies to examine disease burden and the proper allocation of resources.

Indexed as

AlgorithmsClinical CodingDatabases, FactualFemaleHealth Systems PlansHepatitis BHepatitis CHumansInternational Classification of DiseasesLiver CirrhosisMaleMiddle AgedRetrospective Studiesadministrative datahepatitis B virushepatitis C viruspharmacoepidemiologyvalidation

Identifiers

PMID25335773
PMCPMC4293241

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.