Evidence map›Paper›PMID 25335503›Full record

ArticleGenetics2015

Dissecting genetic architecture underlying seed traits in multiple environments.

Ting Qi, Yujie Cao, Liyong Cao, Yongming Gao, Shuijin Zhu, Xiangyang Lou, Haiming Xu

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Ting QiInstitute of Crop Science and Institute of Bioinformatics, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, People's Republic of China.
Yujie CaoInstitute of Crop Science and Institute of Bioinformatics, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, People's Republic of China.
Liyong CaoState Key Laboratory of Rice Biology, China National Rice Research Institute, Hangzhou, 311402, People's Republic of China.
Yongming GaoInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, People's Republic of China.
Shuijin ZhuInstitute of Crop Science and Institute of Bioinformatics, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, People's Republic of China.
Xiangyang LouDepartment of Biostatistics, University of Alabama, Birmingham, Alabama 35294.
Haiming XuInstitute of Crop Science and Institute of Bioinformatics, College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, People's Republic of China hmxu@zju.edu.cn.
Zhejiang University · CNChina National Rice Research Institute · CNInstitute of Crop Sciences · CNUniversity of Alabama at Birmingham · US

Funding

Detection of multifactor interactions with application to nicotine dependenceR01DA025095 · NIDA · UNIVERSITY OF VIRGINIA · PI LOU, XIANG-YANG · 2008 to 2013
$1.1M
NIDA NIH HHS R01 DA025095
6 · The paper itself

Abstract

The seeds of flowering plants develop from double fertilization and play a vital role in reproduction and supplying human and animal food. The genetic variation of seed traits is influenced by multiple genetic systems, e.g., maternal, embryo, and/or endosperm genomes. Understanding the genetic architecture of seed traits is a major challenge because of this complex mechanism of multiple genetic systems, especially the epistasis within or between different genomes and their interactions with the environment. In this study, a statistical model was proposed for mapping QTL with epistasis and QTL-by-environment (QE) interactions underlying endosperm and embryo traits. Our model integrates the maternal and the offspring genomes into one mapping framework and can accurately analyze maternal additive and dominant effects, endosperm/embryo additive and dominant effects, and epistatic effects of two loci in the same or two different genomes, as well as interaction effects of each genetic component of QTL with environment. Intensive simulations under different sampling strategies, heritabilities, and model parameters were performed to investigate the statistical properties of the model. A set of real cottonseed data was analyzed to demonstrate our methods. A software package, QTLNetwork-Seed-1.0.exe, was developed for QTL analysis of seed traits.

Indexed as

Gene-Environment InteractionModels, GeneticQuantitative Trait, HeritableQuantitative Trait LociEnvironmentGenome, PlantGossypiumSeedsSoftwarecrop seed traitsepistasisgene-by-environment interactiongenetic effectmixed linear model

Identifiers

PMID25335503
PMCPMC4286693
OpenAlexW2122054751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.