ArticleEuropean journal of clinical nutrition2015
Omega-3 index levels and associated factors in a middle-aged French population: the MONA LISA-NUT Study.
Article in European journal of clinical nutrition, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Article
- Association of dietary intake of total fat and fatty acids with the Omega-3 Index: a cross-sectional analysis of NHANES 2011-2012.Nutrition research and practice · 2025Article
- Omega-3 fatty acids and major depression: a Mendelian randomization study.Translational psychiatry · 2024Article
- Estimation and predictors of the Omega-3 Index in the UK Biobank.The British journal of nutrition · 2023Article
- Red blood cell fatty acid patterns from 7 countries: Focus on the Omega-3 index.Prostaglandins, leukotrienes, and essential fatty acids · 2022Article
- Higher Omega-3 Index Is Associated with Better Asthma Control and Lower Medication Dose: A Cross-Sectional Study.Nutrients · 2019Article
- The emerging role of omega-3 fatty acids as a therapeutic option in neuropsychiatric disorders.Therapeutic advances in psychopharmacology · 2019Review
- Relationship Between Distance Run Per Week, Omega-3 Index, and Arachidonic Acid (AA)/Eicosapentaenoic Acid (EPA) Ratio: An Observational Retrospective Study in Non-elite Runners.Frontiers in physiology · 2019Article
- Omega-3 Index and Anti-Arrhythmic Potential of Omega-3 PUFAs.Nutrients · 2017Review
- Determinants of polyunsaturated fatty acid concentrations in erythrocytes of pregnant Japanese women from a birth cohort study: study protocol and baseline findings of an adjunct study of the Japan environment & Children's study.Environmental health and preventive medicine · 2017Article
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10 authors.
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Abstract
BACKGROUND/
objectivesThe omega-3 index (the summed percentage content of eicosapentaenoic and docosahexaenoic acids in red blood cells) is associated with a lower risk of fatal coronary heart disease and sudden cardiac death. We aimed to determine which socio-demographic, behavioural or clinical factors are independently associated with the omega-3 index and the extent to which seafood consumption mediates the index's association with socio-economic status (SES). SUBJECTS/
methodsAs part of the cross-sectional MONA LISA-NUT survey (2005-2007), gas chromatography was used to analyse the red blood cell fatty acid composition in 503 French subjects aged 35-64 years. Dietary data were collected by trained dieticians via a validated food frequency questionnaire and a prospective 3-day food record. Risk factors were estimated with standardised measurements and questionnaires. SES was assessed through the self-reported educational and income tax levels.
resultsThe mean ± s.d. omega-3 index was 6.02 ± 1.75%. In the best parsimonious predictive model (which explained 32% of the variability in the omega-3 index), age, educational level and seafood servings were significantly and positively associated with the index. In contrast, waist circumference and smoking were inversely associated with the index. In a mediation analysis that took account of all these factors, seafood servings explained about 40% of the association between educational level and the omega-3 index. Similar results were obtained for the income tax level.
conclusionsThe inverse association between SES and omega-3 index is largely explained (40%) by an insufficient seafood intake. It remains to be seen which other factors mediate this association.
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