ArticleAnatolian journal of cardiology2015
The importance of fragmented QRS in the early detection of cardiac involvement in patients with systemic sclerosis.
Article in Anatolian journal of cardiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Limited Utility of Screening Electrocardiograms in Systemic Sclerosis: Data from the Canadian Scleroderma Research Group.ACR open rheumatology · 2025Article
- Exploring the Impact of Fragmented QRS on Ejection Fraction and Other Echocardiographic Parameters in Systemic Sclerosis Patients: A Retrospective Cohort Study.Research in heart yield and translational medicine · 2025Article
- Progranulin, sICAM-1, and sVCAM-1 May Predict an Increased Risk for Ventricular Arrhythmias in Patients with Systemic Sclerosis.International journal of molecular sciences · 2024Article
- Assessment of QRS duration and presence of fragmented QRS in patients with celiac disease.International journal of medical sciences · 2024Article
- Predicting the Progression of Very Early Systemic Sclerosis: Current Insights.Open access rheumatology : research and reviews · 2022Review
- Electrocardiographic markers for the prediction of ventricular arrhythmias in patients with systemic sclerosis.Rheumatology (Oxford, England) · 2020Review
- Article
- Bundle Branch Blocks and Fragmented QRS Complex in Iranian Patients with Systemic Sclerosis.The journal of Tehran Heart Center · 2019Article
- Fragmented QRS frequency in patients with cardiac syndrome X.Anatolian journal of cardiology · 2016Article
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9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveSystemic sclerosis (SSc) is an autoimmune connective tissue disorder characterized by fibrosis. The prognosis of the disease is bad when clinically symptomatic cardiac dysfunction is occurred, therefore early detection of cardiac dysfunction is important in patients with SSc. The aim of this study was to investigate the frequency of fQRS in superficial electrocardiography in cardiacally asymptomatic patients with SSc and its relation to the systolic pulmonary artery pressure (sPAP).
methodsThis study included 31 cardiacally asymptomatic patients with SSc (23 females, 40.4±9.2 years) and 41 healthy volunteers as the control (31 females, 38.2±11.8 years). The ECGs with 12 derivations and transthoracic echocardiographies of the patients were evaluated. The presence of fQRS in the superficial ECG, and its relation to systolic pulmonary artery pressure (sPAP) were investigated.
resultsThe mean sPAP value in the SSc group was observed to be higher than that of the control group (26 mm Hg and 20 mm Hg, respectively, p<0.001). The presence of fQRS in the SSc group was more frequent than the control group (55% and 10%, respectively, p<0.001). In SSc patients presence of fQRS become relevant with ≥24 mm Hg sPAP by 88% sensitivity and 79% specificity.
conclusionIn our study, the presence of fQRS in SSc patients, were more frequent than in the normal population. Since pulmonary hypertension is the primary cause of mortality in patients with SSc, the correlation of fQRS with sPAP should also be considered.
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