Evidence map›Paper›PMID 25333399›Full record

ArticlePancreas2014

Total pancreatectomy with islet autotransplantation: summary of a National Institute of Diabetes and Digestive and Kidney diseases workshop.

Melena D Bellin, Andres Gelrud, Guillermo Arreaza-Rubin, Ty B Dunn, Abhinav Humar, Katherine A Morgan, Bashoo Naziruddin, Cristiana Rastellini, Michael R Rickels, Sarah J Schwarzenberg and 1 more

Abstract readConference Proceedings
In one paragraph

Article in Pancreas, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 57 citations in OpenAlex.

  1. Observational
  2. Article
  3. Understanding the Structural Arrangement of Islets in Chronic Pancreatitis.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2024
    Article
  4. Article
  5. Review
  6. Single-cell analyses of human pancreas: characteristics of two populations of acinar cells in chronic pancreatitis.American journal of physiology. Gastrointestinal and liver physiology · 2021
    Article
  7. Article
  8. Review
  9. A multicenter study of total pancreatectomy with islet autotransplantation (TPIAT): POST (Prospective Observational Study of TPIAT).Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2018
    Observational
  10. Familial pancreatic cancer: Concept, management and issues.World journal of gastroenterology · 2017
    Review
  11. Article
  12. Article
  13. Hereditary pancreatitis: current perspectives.Clinical and experimental gastroenterology · 2016
    Review
  14. Chronic Pancreatitis and Diabetes Mellitus.Current treatment options in gastroenterology · 2015
    Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Melena D BellinFrom the *Departments of Pediatrics and Surgery, University of Minnesota Medical School, Minneapolis, MN; †The Department of Medicine, Pritzker School of Medicine, Center for Endoscopic Research and Therapeutics, University of Chicago, Chicago, IL; ‡The Divisions of Diabetes, Endocrinology and Metabolism and of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD; §The Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; ∥The Department of Surgery, Medical University of South Carolina, Charleston, SC; ¶Baylor Simmons Transplant Institute, Dallas, TX; #The Department of Surgery, University of Texas Medical Branch, Galveston, TX; and **The Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Andres Gelrud
Guillermo Arreaza-Rubin
Ty B Dunn
Abhinav Humar
Katherine A Morgan
Bashoo Naziruddin
Cristiana Rastellini
Michael R Rickels
Sarah J Schwarzenberg
Dana K Andersen
University of Minnesota Medical Center · USMedical University of South Carolina · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Institutes of Health · USThe University of Texas Medical Branch at Galveston · USUniversity of Chicago · USUniversity of Pittsburgh · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
Sitagliptin therapy to improve outcomes after islet autotransplantation.K23DK084315 · NIDDK · UNIVERSITY OF MINNESOTA · PI BELLIN, MELENA D. · 2010 to 2014
$816k
NCATS NIH HHS UL1 TR000114NIDDK NIH HHS K23 DK084315
6 · The paper itself

Abstract

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases focused on research gaps and opportunities in total pancreatectomy with islet autotransplantation (TPIAT) for the management of chronic pancreatitis (CP). The session was held on July 23, 2014, and structured into 5 sessions: (1) patient selection, indications, and timing; (2) technical aspects of TPIAT; (3) improving success of islet autotransplantation; (4) improving outcomes after total pancreatectomy; and (5) registry considerations for TPIAT. The current state of knowledge was reviewed; knowledge gaps and research needs were specifically highlighted. Common themes included the need to identify which patients best benefit from and when to intervene with TPIAT, current limitations of the surgical procedure, diabetes remission and the potential for improvement, opportunities to better address pain remission, gastrointestinal complications in this population, and unique features of children with CP considered for TPIAT. The need for a multicenter patient registry that specifically addresses the complexities of CP and total pancreatectomy outcomes as well as postsurgical diabetes outcomes was repeatedly emphasized.

Indexed as

AdultAnticoagulantsAnti-Inflammatory AgentsChildDiabetes Mellitus, Type 1EtanerceptHeparinHumansImmunoglobulin GImmunosuppressive AgentsInsulinIslets of Langerhans TransplantationNational Institute of Diabetes and Digestive and Kidney Diseases (U.S.)PancreatectomyPancreatitis, ChronicPatient SelectionAnticoagulantsAnti-Inflammatory AgentsEtanerceptHeparinImmunoglobulin GImmunosuppressive AgentsInsulinReceptors, Tumor Necrosis Factor

Identifiers

PMID25333399
PMCPMC4205476
OpenAlexW2067808140

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.