Evidence map›Paper›PMID 25333384›Full record

SynthesisPloS one2014

Does the method of weight loss effect long-term changes in weight, body composition or chronic disease risk factors in overweight or obese adults? A systematic review.

Richard A Washburn, Amanda N Szabo, Kate Lambourne, Erik A Willis, Lauren T Ptomey, Jeffery J Honas, Stephen D Herrmann, Joseph E Donnelly

Abstract readSystematic Review
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Obesity in South and Southeast Asia-A new consensus on care and management.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Guideline
  2. Pooled it
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  19. Pro12Ala Polymorphism on the PPARFrontiers in physiology · 2020
    Article
  20. NScientific reports · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Richard A WashburnCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Amanda N SzaboCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Kate LambourneCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Erik A WillisCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Lauren T PtomeyCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Jeffery J HonasCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.
Stephen D HerrmannSanford Research, Department of Children's Health Research Center, Sioux Falls, South Dakota, United States of America.
Joseph E DonnellyCardiovascular Research Institute, Department of Internal Medicine, The University of Kansas Medical Center, Kansas City, Kansas, United States of America.

Funding

Prevention of weight regain (POWeR) and cognitive funtionF32DK103493 · NIDDK · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SZABO-REED, AMANDA N. · 2014 to 2016
$172k
NIDDK NIH HHS F32 DK103493
6 · The paper itself

Abstract

backgroundDifferences in biological changes from weight loss by energy restriction and/or exercise may be associated with differences in long-term weight loss/regain.

objectiveTo assess the effect of weight loss method on long-term changes in weight, body composition and chronic disease risk factors. DATA SOURCES: PubMed and Embase were searched (January 1990-October 2013) for studies with data on the effect of energy restriction, exercise (aerobic and resistance) on long-term weight loss. Twenty articles were included in this review. STUDY ELIGIBILITY CRITERIA: Primary source, peer reviewed randomized trials published in English with an active weight loss period of >6 months, or active weight loss with a follow-up period of any duration, conducted in overweight or obese adults were included. STUDY APPRAISAL AND SYNTHESIS

methodsConsiderable heterogeneity across trials existed for important study parameters, therefore a meta-analysis was considered inappropriate. Results were synthesized and grouped by comparisons (e.g. diet vs. aerobic exercise, diet vs. diet + aerobic exercise etc.) and study design (long-term or weight loss/follow-up).

resultsForty percent of trials reported significantly greater long-term weight loss with diet compared with aerobic exercise, while results for differences in weight regain were inconclusive. Diet+aerobic exercise resulted in significantly greater weight loss than diet alone in 50% of trials. However, weight regain (∼ 55% of loss) was similar in diet and diet+aerobic exercise groups. Fat-free mass tended to be preserved when interventions included exercise.

Indexed as

Body CompositionBody WeightWeight LossChronic DiseaseDiet, ReducingExerciseHumansObesityOverweightRisk Factors

Identifiers

PMID25333384
PMCPMC4198137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.