Evidence map›Paper›PMID 25333345›Full record

ArticlePloS one2014

Relationship between lifestyle and health factors and severe lower urinary tract symptoms (LUTS) in 106,435 middle-aged and older Australian men: population-based study.

David P Smith, Marianne F Weber, Kay Soga, Rosemary J Korda, Gabriella Tikellis, Manish I Patel, Mark S Clements, Terry Dwyer, Isabel K Latz, Emily Banks

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Self-management of male urinary symptoms: qualitative findings from a primary care trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026
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  10. Non-linear Relationship Between Body Mass Index and Lower Urinary Tract Symptoms in Korean Males.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

David P SmithCancer Research Division, Cancer Council NSW, Sydney, New South Wales, Australia; Griffith Health Institute, Griffith University, Gold Coast, Queensland, Australia.
Marianne F WeberGriffith Health Institute, Griffith University, Gold Coast, Queensland, Australia; School of Public Health, Sydney University, Sydney, New South Wales, Australia.
Kay SogaNational Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.
Rosemary J KordaNational Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.
Gabriella TikellisMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Manish I PatelSchool of Public Health, Sydney University, Sydney, New South Wales, Australia.
Mark S ClementsKarolinska Institute, Stockholm, Sweden.
Terry DwyerMurdoch Childrens Research Institute, Melbourne, Victoria, Australia.
Isabel K LatzFielding School of Public Health, University of California Los Angeles, Los Angeles, California, United States of America.
Emily BanksThe Sax Institute, Sydney, New South Wales, Australia; National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australian Capital Territory, Australia.
Australian National University · AUMurdoch Children's Research Institute · AUUniversity of Sydney · AUGriffith University · AUKarolinska Institutet · SEUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite growing interest in prevention of lower urinary tract symptoms (LUTS) through better understanding of modifiable risk factors, large-scale population-based evidence is limited.

objectiveTo describe risk factors associated with severe LUTS in the 45 and Up Study, a large cohort study. DESIGN, SETTING, AND

participantsA cross-sectional analysis of questionnaire data from 106,435 men aged ≥ 45 years, living in New South Wales, Australia. OUTCOME MEASURES AND STATISTICAL ANALYSIS: LUTS were measured by a modified version of the International Prostate Symptom Score (m-IPSS). The strength of association between severe LUTS and socio-demographic, lifestyle and health-related factors was estimated, using logistic regression to calculate odds ratios, adjusted for a range of confounding factors.

resultsOverall, 18.3% reported moderate, and 3.6% severe, LUTS. Severe LUTS were more common among men reporting previous prostate cancer (7.6%), total prostatectomy (4.9%) or having part of the prostate removed (8.2%). After excluding men with prostate cancer or prostate surgery, the prevalence of moderate-severe LUTS in the cohort (n = 95,089) ranged from 10.6% to 35.4% for ages 45-49 to ≥ 80; the age-related increase was steeper for storage than voiding symptoms. The adjusted odds of severe LUTS decreased with increasing education (tertiary qualification versus no school certificate, odds ratio (OR = 0.78 (0.68-0.89))) and increasing physical activity (high versus low, OR = 0.83 (0.76-0.91)). Odds were elevated among current smokers versus never-smokers (OR = 1.64 (1.43-1.88)), obese versus healthy-weight men (OR = 1.27 (1.14-1.41)) and for comorbid conditions (e.g., heart disease versus no heart disease, OR = 1.36 (1.24-1.49)), and particularly for severe versus no physical functional limitation (OR = 5.17 (4.51-5.93)).

conclusionsLUTS was associated with a number of factors, including modifiable risk factors, suggesting potential targets for prevention.

Indexed as

Life StyleAgedAged, 80 and overAustraliaCohort StudiesCross-Sectional StudiesHealth SurveysHumansLower Urinary Tract SymptomsMaleMiddle AgedPrevalenceProstatectomyProstatic NeoplasmsRisk FactorsSeverity of Illness Index

Identifiers

PMID25333345
PMCPMC4198085
OpenAlexW2009056698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.