ArticleAnnals of translational medicine2014
β(1-3)(1-6)-D-glucans modulate immune status in pigs: potential importance for efficiency of commercial farming.
Article in Annals of translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 38 citations in OpenAlex.
- Amino Acid Nutrition in Poultry: A Review.Animals : an open access journal from MDPI · 2025Review
- Impact of Selected Natural Bioactive Substances on Immune Response and Tight Junction Proteins in Broiler Chickens.Veterinary medicine and science · 2025Article
- Effects of β-glucan with vitamin E supplementation on the physiological response, litter performance, blood profiles, immune response, and milk composition of lactating sows.Animal bioscience · 2023Article
- Effect of 1,3-Beta Glucans Dietary Addition on the Growth, Intestinal Histology, Blood Biochemical Parameters, Immune Response, and Immune Expression of CD3 and CD20 in Broiler Chickens.Animals : an open access journal from MDPI · 2022Article
- Applications of Probiotic-Based Multi-Components to Human, Animal and Ecosystem Health: Concepts, Methodologies, and Action Mechanisms.Microorganisms · 2022Review
- Review: β-glucans as Effective Antibiotic Alternatives in Poultry.Molecules (Basel, Switzerland) · 2021Review
- Inclusion of Oat and Yeast Culture in Sow Gestational and Lactational Diets Alters Immune and Antimicrobial Associated Proteins in Milk.Animals : an open access journal from MDPI · 2021Article
- Yeast β-Glucan Altered Intestinal Microbiome and Metabolome in Older Hens.Frontiers in microbiology · 2021Article
- Dietary supplementation of beta-glucan-rich molasses yeast powder on antibody response to swine fever virus and hematology of starter-grower pigs.Tropical animal health and production · 2020Article
- Development of Fish Immunity and the Role of β-Glucan in Immune Responses.Molecules (Basel, Switzerland) · 2020Review
- Impact of Yeast-Derived β-Glucans on the Porcine Gut Microbiota and Immune System in Early Life.Microorganisms · 2020Article
- Effects of Dietary Inclusion of Seaweed, Heat Stress and Genetic Strain on Performance, Plasma Biochemical and Hematological Parameters in Laying Hens.Animals : an open access journal from MDPI · 2020Article
- Effect of Carotenoids, Oligosaccharides and Anthocyanins on Growth Performance, Immunological Parameters and Intestinal Morphology in Broiler Chickens Challenged withAnimals : an open access journal from MDPI · 2020Article
- Innate Immunomodulation in Food Animals: Evidence for Trained Immunity?Frontiers in immunology · 2020Review
- Major cereal carbohydrates in relation to intestinal health of monogastric animals: A review.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2019Review
- Effects of dietary supplementation with different levels and molecular weights of fungal β-glucan on performances, health and meat quality in broilersAsian-Australasian journal of animal sciences · 2019Article
- Effects of dietary yeast beta-1,3-1,6-glucan on growth performance, intestinal morphology and chosen immunity parameters changes in Haidong chicks.Asian-Australasian journal of animal sciences · 2019Article
- β-Glucan and Parasites.Helminthologia · 2018Article
- Supplementing the feeds of layer pullets, at different ages with two different fiber sources improves immune function.Poultry science · 2017Article
- Administration ofThe journal of poultry science · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn face of the challenge of the emergent diseases and the current efforts of the governments to create conditions to ban growth-promoting antibiotics and to improve efficiency of the commercial farming, new opportunities are created for natural, highly effective and cost affordable immunomodulators; able to induce and enhance resistance against diseases and to reduce farming-related stress. Supplementation of animal feed with β(1-3)(1-6)-D-glucans has been repeatedly shown to modulate the immune system ant to influence growth characteristics of farmed animals. MATERIALS AND
methodsIn our study we focused on evaluation of effects of an insoluble, fungi-derived β(1-3)(1-6)-D-glucan as dietary supplement in piglets. We measured the growth, phagocytosis of peripheral blood cells and interleukin 2 (IL-2) and tumor necrosis factor alpha (TNF-α) production after feeding with 15 mg of glucan/kg/day.
conclusionsFollowing supplementation, β(1-3)(1-6)-D-glucan has been shown to stimulate growth, phagocytic activity, and IL-2 production. In addition, it significantly lowered the cortisol and TNF-α levels after lipopolysaccharide (LPS) challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.