ReviewAnnals of translational medicine2014
Vitamin D and GI cancers: shedding some light on dark diseases.
Review in Annals of translational medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Importance of vitamin D in gastrointestinal health and disease.Frontiers in nutrition · 2026Review
- The role of vitamin D in gastrointestinal cancer prevention and management: a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Dietary vitamin D and gastric cancer risk within the stomach cancer pooling (stop) project.European journal of nutrition · 2025Article
- Article
- Simultaneous determination of vitamin D metabolites 25(OH)DJournal of mass spectrometry and advances in the clinical lab · 2022Article
- Relevance of vitamin DGene reports · 2021Review
- Vitamin D and Gastric Cancer: A Ray of Sunshine?Cureus · 2021Review
- Micronutrient Food Supplements in Patients with Gastro-Intestinal and Hepatic Cancers.International journal of molecular sciences · 2021Review
- Chemoprevention in Barrett's esophagus and esophageal adenocarcinoma.Therapeutic advances in gastroenterology · 2021Review
- Role of Vitamin D in Colorectal Cancer: A Holistic Approach and Review of the Clinical Utility.Cureus · 2020Review
- 1,25-Dihydroxyvitamin DOncoTargets and therapy · 2019Article
- Vitamin D receptor as a marker of prognosis in oesophageal adenocarcinoma: a prospective cohort study.Oncotarget · 2018Article
- Pathogenic roles of alterations in vitamin D and vitamin D receptor in gastric tumorigenesis.Oncotarget · 2017Review
- Association between serum vitamin D levels and gastric cancer: A retrospective chart analysis.World journal of gastrointestinal oncology · 2016Article
- Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.Pharmacological research · 2016Review
- Clinicopathological features, vitamin D serological levels and prognosis in cutaneous melanoma of shield-sites: an update.Medical oncology (Northwood, London, England) · 2015Observational
- Possible role of vitamin D3 on the adipocyte/fibroblast trans-differentiation mediated by pancreas cancerCurrent health sciences journalArticle
- Vitamin D and gastrointestinal cancer.Journal of laboratory physiciansReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
vitamin d synthesis and signaling affects numerous cellular processes includingproliferation, differentiation and apoptosis. It is now commonly recognized that low levels of vitamin D are associated with a greater risk of tumorigenesis. Cancers of the gastrointestinal tract are most often difficult to diagnose and treat as patients typically present with progressed disease. Basic research, clinical trials and population studies have supported the concept that treatment with Vitamin D may be a therapeutic option when treating GI cancers, however treatments must be individualized and monitored closely as the side effects from Vitamin D treatment can be increasingly harmful. This review will highlight the most recent findings regarding Vitamin D signaling and GI cancers.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.