Evidence map›Paper›PMID 25332916›Full record

ReviewWorld journal of methodology2014

Dyspepsia and celiac disease: Prevalence, diagnostic tools and therapy.

Laura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Manuela Brighi, Stefano Pontone

Open access · hybridAbstract readReview
In one paragraph

Review in World journal of methodology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Celiac disease in non-clinical populations of Japan.Journal of gastroenterology · 2018
    Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Laura PetrarcaLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Raffaella NennaLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Gerarda MastrogiorgioLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Matteo FlorioLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Manuela BrighiLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Stefano PontoneLaura Petrarca, Raffaella Nenna, Gerarda Mastrogiorgio, Matteo Florio, Department of Pediatrics, "Sapienza" University of Rome, 00161 Rome, Italy.
Sapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prevalence of dyspepsia is up to 40% in population-based study. Functional dyspepsia is an exclusion diagnosis and it is classified as a chronic abdominal pain-related functional disorder, characterized by the presence of persistent or recurrent pain or discomfort centered in the upper abdomen, neither relief by defecation, nor association with the onset of a change in stool frequency or form. Celiac disease (CD) is a common autoimmune enteropathy, with a prevalence around 1% in the general population. Its diagnosis includes a serological screening and an upper gastrointestinal endoscopy with multiple biopsies. Gluten-free diet is the only effective treatment. CD diagnosis is often delayed in asymptomatic patients or in individuals with less clinical gastrointestinal symptoms. Several studies performed coeliac disease screening in patients with symptoms suggestive of dyspepsia, showing a biopsy-proved prevalence that ranged from 0.5% to 2%. The typical endoscopic markers of villous atrophy are not sufficiently sensitive, so some endoscopic techniques, such as "water immersion" and confocal endomicroscopy were proposed to improve the diagnostic sensitivity and target biopsies. A recent meta-analysis estimated that the prevalence of CD was higher in patients with dyspepsia, but not in a statistically significant way. However this assumption should be confirmed further larger studies.

Indexed as

Coeliac diseaseDyspepsiaScreeningUpper endoscopyVillus atrophy

Identifiers

PMID25332916
PMCPMC4202456
OpenAlexW2071507349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.