Evidence map›Paper›PMID 25332840›Full record

ArticleCellular logistics2013

Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes.

Paul A Randazzo, Xiaoying Jian, Pei-Wen Chen, Peng Zhai, Olivier Soubias, John K Northup

Open access · bronzeAbstract read
In one paragraph

Article in Cellular logistics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. The citron homology domain as a scaffold for Rho1 signaling.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Paul A RandazzoLaboratory of Cellular and Molecular Biology; National Cancer Institute; Bethesda, MD USA.
Xiaoying JianLaboratory of Cellular and Molecular Biology; National Cancer Institute; Bethesda, MD USA.
Pei-Wen ChenLaboratory of Cellular and Molecular Biology; National Cancer Institute; Bethesda, MD USA.
Peng ZhaiLaboratory of Cellular and Molecular Biology; National Cancer Institute; Bethesda, MD USA.
Olivier SoubiasLaboratory of Membrane Biochemistry and Biophysics; National Institute on Alcohol Abuse and Alcoholism; Rockville, MD USA.
John K NorthupLaboratory of Membrane Biochemistry and Biophysics; National Institute on Alcohol Abuse and Alcoholism; Rockville, MD USA.
National Cancer Institute · USNational Institute on Alcohol Abuse and Alcoholism · US

Funding

REGULATION OF ADP-RIBOSYLATION FACTORZ01BC007365 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI RANDAZZO, PAUL A · 1996 to 2008
$3.3M
Intramural NIH HHS Z01 BC007365
6 · The paper itself

Abstract

The proteins that possess guanine nucleotide exchange factor (GEF) activity, which include about ~800 G protein coupled receptors (GPCRs),

Indexed as

G protein coupled receptorsGTP-binding proteinguanine nucleotide exchange factorsHeterotrimeric G proteinsRas superfamily

Identifiers

PMID25332840
PMCPMC4187004
OpenAlexW2071036734

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.