ArticleOpen heart
Percutaneous left atrial appendage occlusion for stroke prevention in atrial fibrillation: an update.
Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Design and Validation of a High-Fidelity Left Atrial Cardiac Simulator for the Study and Advancement of Left Atrial Appendage Occlusion.Cardiovascular engineering and technology · 2025Article
- Systematic review and meta-analysis of left atrial appendage closure's influence on early and long-term mortality and stroke.JTCVS open · 2024Article
- Transcatheter Left Atrial Appendage Closure.Methodist DeBakey cardiovascular journal · 2023Article
- JCS/JHRS 2019 guideline on non-pharmacotherapy of cardiac arrhythmias.Journal of arrhythmia · 2021Article
- Large Device-Related Thrombus Detected following Symptoms of Transient Ischemic Attack.Case reports in cardiology · 2021Article
- Short-Term Apixaban for Documented Left Atrial Appendage Thrombus in High-Risk Atrial Fibrillation Patients Undergoing Left Atrial Appendage Occlusion.TH open : companion journal to thrombosis and haemostasis · 2020Article
- Comparison of echocardiographic and fluoroscopic sizing of the left atrial appendage prior to percutaneous closure.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020Article
- Article
- The value of the left atrial appendage orifice perimeter of 3D model based on 3D TEE data in the choice of device size of LAmbre™ occluder.The international journal of cardiovascular imaging · 2019Article
- Successful left atrial appendage closure in a patient with prior patent foramen ovale occlusion.HeartRhythm case reports · 2019Article
- Two-dimensional versus three-dimensional transesophageal echocardiography in percutaneous left atrial appendage occlusion.Cardiology journal · 2019Article
- Current State of Left Atrial Appendage Closure.Current cardiology reports · 2018Review
- Evaluating the morphology of the left atrial appendage by a transesophageal echocardiographic 3-dimensional printed model.Medicine · 2017Article
- Left atrial appendage occlusion: A better alternative to anticoagulation?World journal of cardiology · 2017Review
- Novel stroke risk reduction in atrial fibrillation: left atrial appendage occlusion with a focus on the Watchman closure device.Vascular health and risk management · 2017Review
- Where We Stand on Left Atrial Appendage Closure for Stroke Prevention in Atrial Fibrillation.Texas Heart Institute journal · 2016Article
- Heart Rhythm Monitoring Strategies for Cryptogenic Stroke: 2015 Diagnostics and Monitoring Stroke Focus Group Report.Journal of the American Heart Association · 2016Review
- Heart within a Heart.Journal of cardiovascular ultrasound · 2016Article
- Predicting Peri-Device Leakage of Left Atrial Appendage Device Closure Using Novel Three-Dimensional Geometric CT Analysis.Journal of cardiovascular ultrasound · 2015Article
- Early results of first versus second generation Amplatzer occluders for left atrial appendage closure in patients with atrial fibrillation.Clinical research in cardiology : official journal of the German Cardiac Society · 2015Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia encountered in clinical practice. One of its most devastating complications is the development of thromboembolism leading to fatal or disabling stroke. Oral anticoagulation (OAC, warfarin) is the standard treatment for stroke prevention in patients with AF with an increased stroke risk. However, there are several obstacles to long-term OAC therapy, including the risk of serious bleeding, several drug-drug interactions and the need for frequent blood testing. Although newer oral anticoagulants have been developed, these drugs also face issues of major bleeding and non-compliance. Therefore, alternative treatment options for stroke prevention in patients with AF with a high stroke risk are needed. Percutaneous left atrial appendage (LAA) occlusion is an evolving therapy, which should be taken into consideration in those patients with non-valvular AF with a high stroke risk and contraindications for OAC. This article aims to discuss the rationale for LAA closure, the available LAA occlusion devices and their clinical evidence until now. Moreover, we discuss the importance of proper patient selection, the role of various imaging techniques and the need for a more tailored postprocedural antithrombotic therapy.
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