Evidence map›Paper›PMID 25332399›Full record

ArticleNucleic acids research2015

Mouse Tumor Biology (MTB): a database of mouse models for human cancer.

Carol J Bult, Debra M Krupke, Dale A Begley, Joel E Richardson, Steven B Neuhauser, John P Sundberg, Janan T Eppig

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 54 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  5. The Mouse Models of Human Cancer database (MMHCdb).Disease models & mechanisms · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Using Mouse andInternational journal of molecular sciences · 2018
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Carol J BultThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA carol.bult@jax.org.
Debra M KrupkeThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
Dale A BegleyThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
Joel E RichardsonThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
Steven B NeuhauserThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
John P SundbergThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
Janan T EppigThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME, USA.
Jackson Laboratory · US

Funding

Shared Resource ManagementP30CA034196 · NCI · JACKSON LABORATORY · PI William Carl Skarnes · 1985 to 2026
$61.9M
Mouse Models of Human Cancer DatabaseR01CA089713 · NCI · JACKSON LABORATORY · PI BULT, CAROL J · 2002 to 2025
$17.5M
NCI NIH HHS CA089713NCI NIH HHS P30 CA034196NCI NIH HHS P30CA034196NCI NIH HHS R01 CA089713
6 · The paper itself

Abstract

The Mouse Tumor Biology (MTB; http://tumor.informatics.jax.org) database is a unique online compendium of mouse models for human cancer. MTB provides online access to expertly curated information on diverse mouse models for human cancer and interfaces for searching and visualizing data associated with these models. The information in MTB is designed to facilitate the selection of strains for cancer research and is a platform for mining data on tumor development and patterns of metastases. MTB curators acquire data through manual curation of peer-reviewed scientific literature and from direct submissions by researchers. Data in MTB are also obtained from other bioinformatics resources including PathBase, the Gene Expression Omnibus and ArrayExpress. Recent enhancements to MTB improve the association between mouse models and human genes commonly mutated in a variety of cancers as identified in large-scale cancer genomics studies, provide new interfaces for exploring regions of the mouse genome associated with cancer phenotypes and incorporate data and information related to Patient-Derived Xenograft models of human cancers.

Indexed as

Databases, GeneticDisease Models, AnimalAnimalsGenomicsInternetMiceNeoplasms, ExperimentalQuantitative Trait Loci

Identifiers

PMID25332399
PMCPMC4384039
OpenAlexW2090559761

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.