Evidence map›Paper›PMID 25332217›Full record

ArticleReproductive sciences (Thousand Oaks, Calif.)2015

Unbiased and efficient estimation of the volume of the fibroid uterus using the Cavalieri method and magnetic resonance imaging.

Michael J Thrippleton, Kirsty I Munro, Graham McKillop, David E Newby, Ian Marshall, Neil Roberts, Hilary O D Critchley

Abstract readComparative Study
In one paragraph

Article in Reproductive sciences (Thousand Oaks, Calif.), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Selective progesterone receptor modulators (SPRMs) for uterine fibroids.The Cochrane database of systematic reviews · 2017
    Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael J ThrippletonCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Kirsty I MunroMRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom.
Graham McKillopDepartment of Radiology, Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
David E NewbyCentre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Ian MarshallCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, United Kingdom Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom.
Neil RobertsClinical Research Imaging Centre, (CRIC) University of Edinburgh, Edinburgh, United Kingdom.
Hilary O D CritchleyMRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom hilary.critchley@ed.ac.uk.

Funding

Medical Research Council G1002033Wellcome Trust 103782
6 · The paper itself

Abstract

The aim of our study was to develop a reliable technique for measuring volume of the fibroid uterus using Magnetic Resonance Imaging. We applied the Cavalieri method and standard calliper technique to measure the volume of the uterus and largest fibroid in 26 patients, and results were compared with "gold-standard" planimetry measurements. We found Cavalieri measurements to be unbiased, while calliper measurements systematically underestimated uterine volume (- 13.2%, P < 10(-5)) and had greater variance. Repeatability was similar for the 2 techniques (standard deviation [SD] = 4.0%-6.9%). Reproducibility of Cavalieri measurements was higher for measurement of uterine (SD = 9.0%) than fibroid volume (SD = 19.1%), whereas the reproducibility of calliper measurements was higher for fibroid (SD = 9.1%) than uterine volume (SD = 15.9%). The additional measurement time for the Cavalieri method was approximately 1 to 2 minutes. In conclusion, the Cavalieri method permits more accurate measurement of uterine and fibroid volumes and is suitable for application in both clinical practice and scientific research.

Indexed as

Magnetic Resonance ImagingTumor BurdenFemaleHumansImage Interpretation, Computer-AssistedLeiomyomaObserver VariationPredictive Value of TestsReproducibility of ResultsUterine Neoplasmsfibroid uterusleiomyomaMagnetic Resonance Imagingvolume estimation

Identifiers

PMID25332217
PMCPMC4275452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.