ArticleProceedings of the National Academy of Sciences of the United States of America2014
Compartmentalization of the protein repair machinery in photosynthetic membranes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 95 citations in OpenAlex.
- From proton microdomains to protein migration: hypothesis for ΔpH-controlled PSII relocation.Photosynthesis research · 2026Article
- Tropical forest trees with higher thermal optima of photosynthesis exhibit lower PSII heat stability.Journal of experimental botany · 2026Article
- Ionic regulation of thylakoid membrane architecture: Mg2+-driven destacking and restacking visualized.Plant physiology · 2026Article
- How state transitions balance photosynthetic electron transport in plants - a quantitative study.The New phytologist · 2026Article
- What are grana in chloroplasts of vascular plants good for?Annals of botany · 2026Review
- Unraveling design principles of protein landscapes in photosynthetic membranes in plant chloroplasts.Science advances · 2026Article
- Thylakostasis: key factors in thylakoid membrane organization with emphasis on biogenesis and remodeling proteins in vascular plants.Plant & cell physiology · 2025Review
- Article
- Shrink or expand? Just relax! Bidirectional grana structural dynamics as early light-induced regulator of photosynthesis.The New phytologist · 2025Article
- Defining the heterogeneous composition of Arabidopsis thylakoid membrane.The Plant journal : for cell and molecular biology · 2025Article
- Localization of proteins involved in the biogenesis and repair of the photosynthetic apparatus to thylakoid subdomains inPlant direct · 2024Article
- CO-EXPRESSED WITH PSI ASSEMBLY1 (CEPA1) is a photosystem I assembly factor in Arabidopsis.The Plant cell · 2024Article
- The biogenesis and maintenance of PSII: Recent advances and current challenges.The Plant cell · 2024Review
- Liquid-Liquid Phase Separation-Mediated Photocatalytic Subcellular Hybrid System for Highly Efficient Hydrogen Production.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Thylakoid membrane stacking controls electron transport mode during the dark-to-light transition by adjusting the distances between PSI and PSII.Nature plants · 2024Article
- Proximity to Photosystem II is necessary for activation of Plastid Terminal Oxidase (PTOX) for photoprotection.Nature communications · 2024Article
- Protein assemblies in theFrontiers in plant science · 2024Article
- Bicarbonate activation of the monomeric photosystem II-PsbS/Psb27 complex.Plant physiology · 2023Article
- Structure ofeLife · 2023Article
- De-etiolation-induced protein 1 (DEIP1) mediates assembly of the cytochrome bNature communications · 2022Article
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A crucial component of protein homeostasis in cells is the repair of damaged proteins. The repair of oxygen-evolving photosystem II (PS II) supercomplexes in plant chloroplasts is a prime example of a very efficient repair process that evolved in response to the high vulnerability of PS II to photooxidative damage, exacerbated by high-light (HL) stress. Significant progress in recent years has unraveled individual components and steps that constitute the PS II repair machinery, which is embedded in the thylakoid membrane system inside chloroplasts. However, an open question is how a certain order of these repair steps is established and how unwanted back-reactions that jeopardize the repair efficiency are avoided. Here, we report that spatial separation of key enzymes involved in PS II repair is realized by subcompartmentalization of the thylakoid membrane, accomplished by the formation of stacked grana membranes. The spatial segregation of kinases, phosphatases, proteases, and ribosomes ensures a certain order of events with minimal mutual interference. The margins of the grana turn out to be the site of protein degradation, well separated from active PS II in grana core and de novo protein synthesis in unstacked stroma lamellae. Furthermore, HL induces a partial conversion of stacked grana core to grana margin, which leads to a controlled access of proteases to PS II. Our study suggests that the origin of grana in evolution ensures high repair efficiency, which is essential for PS II homeostasis.
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