Evidence map›Paper›PMID 25331853›Full record

Trial reportInternational journal of behavioral medicine2015

Application of Latent Class Analysis to Identify Behavioral Patterns of Response to Behavioral Lifestyle Interventions in Overweight and Obese Adults.

Stephanie L Fitzpatrick, Janelle W Coughlin, Lawrence J Appel, Crystal Tyson, Victor J Stevens, Gerald J Jerome, Arlene Dalcin, Phillip J Brantley, Felicia Hill-Briggs

Abstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in International journal of behavioral medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
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  11. Article
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  14. Predictors of Long-Term Adherence to Multiple Health Behavior Recommendations for Weight Management.Health education & behavior : the official publication of the Society for Public Health Education · 2018
    Article
  15. Article
  16. CKD Self-management: Phenotypes and Associations With Clinical Outcomes.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2018
    Article
  17. Article
  18. Identifying Patterns of Lifestyle Behaviors among People with Type 2 Diabetes in Tianjin, China: A Latent Class Analysis.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2017
    Article
  19. Review
  20. Adaptive Interventions in Child and Adolescent Mental Health.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephanie L FitzpatrickDepartment of Preventive Medicine, Rush University Medical Center, 1700 W. Van Buren St., Room 478A, Chicago, IL, 60607, USA, Stephanie_Fitzpatrick@rush.edu.
Janelle W Coughlin
Lawrence J Appel
Crystal Tyson
Victor J Stevens
Gerald J Jerome
Arlene Dalcin
Phillip J Brantley
Felicia Hill-Briggs

Funding

WEIGHT LOSS MAINTENANCE TRIALU01HL068955 · NHLBI · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI BRANTLEY, PHILLIP J · 2003 to 2007
$2.3M
NHLBI NIH HHS U01 HL068955
6 · The paper itself

Abstract

backgroundExamining responders and non-responders to behavioral lifestyle interventions among overweight/obese adults with additional comorbidities may aid in refining and tailoring obesity treatment. PURPOSE: The purpose of this study is to demonstrate the use of latent class analysis to identify patterns of response to behavioral lifestyle interventions based on adherence to diet and exercise recommendations.

methodRepeated measures latent class analysis was applied to two clinical trial datasets, combination of two active interventions in the PREMIER Trial (n = 501) and phase 1 of the Weight Loss Maintenance Trial (WLM; n = 1685), to identify patterns of response to behavioral lifestyle interventions. Treatment response was based on adherence to daily recommendations for fruit/vegetable, fat, saturated fat, sodium, and exercise at baseline and 6 months.

resultsIn PREMIER, three distinct latent classes emerged: responders (45.9%), non-responders (23.6%), and early adherers (30.5%). Responders and Early Adherers had greater weight loss at 6 and 18 months and were more likely to meet behavioral recommendations at 18 months than Non-responders. For WLM, there were four latent classes: partial responders (16%), non-responders (40%), early adherers (2%), and fruit/veggie only responders (41%). Non-responders in WLM had significantly less weight loss at 6 months compared to that of the other three latent classes.

conclusionLatent class analysis is a useful method to apply to clinical trial data to identify distinct patterns of response to behavioral interventions. Overweight/ obese participants who respond to behavioral lifestyle treatment (i.e., meet behavioral recommendations) have significantly greater weight loss than that of participants who do not make behavioral changes.

Indexed as

Life StyleAdultBehavior TherapyDietExerciseFemaleHumansMaleObesityOverweightWeight Loss

Identifiers

PMID25331853
PMCPMC4957646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.